Privacy-protecting multivariable-adjusted distributed regression analysis for multi-center pediatric study.

CONCLUSIONS: We demonstrated empirically the feasibility and validity of distributed linear regression analysis using only summary-level information within a large multi-center study of children. This approach could enable expanded opportunities for multi-center pediatric research, especially when sharing of granular individual-level data is challenging.
PMID: 31578038 [PubMed - as supplied by publisher]

Source: Pediatric Research - October 1, 2019 Category: Pediatrics Authors: Toh S, Rifas-Shiman SL, Lin PI, Bailey LC, Forrest CB, Horgan CE, Lunsford D, Moyneur E, Sturtevant JL, Young JG, Block JP, PCORnet Antibiotics and Childhood Growth Study Group Tags: Pediatr Res Source Type: research