Protective effect of hydrogen sulfide on monocrotaline ‑induced pulmonary arterial hypertension via inhibition of the endothelial mesenchymal transition.

In conclusion, the current study provides novel information elucidating the beneficial effect of H2S on PAH through inhibiting the induction of the NF‑κB‑Snail pathway and the subsequent process of EndMT in pulmonary arteries.
PMID: 31573044 [PubMed - as supplied by publisher]

Source: International Journal of Molecular Medicine - September 30, 2019 Category: Molecular Biology Authors: Zhang H, Lin Y, Ma Y, Zhang J, Wang C, Zhang H Tags: Int J Mol Med Source Type: research