Ombudsman probes failings of its own investigation

The Parliamentary Health Service Ombudsman has launched a review of failings in relation to an investigation into the death of a young woman with anorexia, HSJ has learned.
Source: HSJ - Category: UK Health Source Type: news

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Conclusions When managing patients with decades-long disease and multiple comorbidities, clinicians must be realistic about the low odds of effecting cure and adjust treatment expectations accordingly. For patients with SE-AN, a variety of low-intensity treatment approaches, at times extending to palliative and hospice care, may be useful. Clinicians should always strive to provide humane comfort and support, as closely aligned to patients' judicious wishes as realistically possible.
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
The present research examined a model that evaluates the mediating role of both intrapersonal and interpersonal emotional competences (ECs) between attachment insecurity and the cognitive and emotional dimensions of empathy in patients with anorexia nervosa (AN). Women with AN completed the Experiences in Close Relationships Scale, the Profile of Emotional Competence, the Interpersonal Reactivity Index, the State-Trait Anxiety Inventory, and the Beck Depression Inventory. The results revealed that intrapersonal EC mediated the relationships between attachment insecurity (i.e., attachment anxiety and attachment avoidance) a...
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
ConclusionNapabucasin was well-tolerated at doses up to 1440  mg/day in Japanese patients with advanced solid tumors; the PK profile was comparable to that reported previously.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research
In conclusion, we show that BMAT is inversely associated with WBC and RBC in premenopausal women, and there is a potential association between longitudinal changes in BMAT and changes in RBC. These associations warrant further study and may provide further insight into the role and function of this understudied adipose depot. © 2020 American Society for Bone and Mineral Research.
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
Evaluation of the action of various traditional plants to treat metabolic syndrome are strongly studied. In our study, we investigated the effect of the Tunisian jojoba seed on a metabolic syndrome induced in ...
Source: Nutrition and Metabolism - Category: Nutrition Authors: Tags: Research Source Type: research
AbstractThis commentary justifies the need for the Australian government to address stigma and shame in its effort to increase help-seeking by individuals with eating disorders from the intersectional perspective of a health consumer with a history of anorexia nervosa and a public health researcher. It does so in response to the government ’s planned 2019 investment of $110 million to subsidise eating disorders treatment services. The commentary identifies stigma and shame as the leading barrier to help-seeking among individuals with eating disorders. It then uses peer-reviewed evidence and analyses of popular press ...
Source: Journal of Eating Disorders - Category: Eating Disorders & Weight Management Source Type: research
Hypothalamic amenorrhea is common in adolescents and young adults (AYAs) with anorexia nervosa (AN), and ovarian reserve is not routinely assessed as part of routine clinical care. Multiple neuroendocrine alterations occur with AN, and appear to impair reproductive health. AN leads to higher rates of fertility problems, later age at childbearing, and increased rates of obstetrical complications. How or when AN negatively influences future fertility is unclear. We sought to determine whether biomarkers of ovarian reserve were impacted in AYA with AN.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
Anorexia Nervosa Genetics Initiative (ANGI)  (study page |release notes)
Source: dbGaP, the database of Genotypes and Phenotypes - Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research
I was diagnosed with anorexia nervosa over a decade ago. Blinded by the eating disorder to the damage that was occurring both internally and externally, the possibility of infertility did not occur to me. When I married at 21, my husband and I both dreamed of one day becoming parents and I lived in this optimism for some time. However, after my periods stopped for 7 years, I began to doubt if being a mother would ever be my reality.  As an eating disorder patient, I had been regularly informed of the risk factors of my illness, some of which included amenorrhoea, the absence of menstruation, and a high chance of infer...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anorexia Eating Disorders Personal Pregnancy Infertility Source Type: blogs
ConclusionWeekly 5-FU –leucovorin with biweekly bevacizumab may be a tolerable and effective treatment option for older or frail patients with mCRC.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
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