How to Take Care of Your Eyes as You Age: be aware of GMC: Glaucoma, Macular degeneration, Cataract

FromConsumer Reports:GlaucomaMore than 2 million Americans have glaucoma, but 50% know it. Glaucoma often goes undiagnosed because it causes no symptoms until vision declines, at which point treatment no longer helps.People aged 40-60 should be examined by an optometrist every 3-5 years; those older than 60 need an eye exam every 1-2 years.Many eye doctors screen for glaucoma with tonometry (measures eye pressure) but that ’s not enough. Relying only on intraocular pressure (IOP) when screening for glaucoma could miss up to 50% of all cases. Theexam should also include an ophthalmoscopy, which involves examining your optic nerve.The most common treatment for glaucoma is eye drops known asprostaglandin analogs (PGAs),which lower eye pressure. Generic versions of most of those drugs are much cheaper than the brand-name versions.Age-related Macular Degeneration (AMD)There are two main forms of AMD:1.Dry AMD, more common variety, which is treated mainly with dietary supplementsA specific blend of vitamins and minerals known as AREDS (vitamins C and E, plus copper, lutein, zeaxanthin, and zinc) lowers the risk of dry AMD progression by 25%. It ’s the only treatment as of 2019.Not all eye supplements contain the proper formulation. In an analysis of 11 eye-health supplements, only 4 contained the right mix: PreserVision Eye Vitamin AREDS Formula, PreserVision Eye Vitamin Lutein Formula, PreserVision AREDS2 Formula, and ICAPS AREDS.Don ’t bother taking an...
Source: Clinical Cases and Images - Blog - Category: Universities & Medical Training Tags: Ophthalmology Source Type: blogs

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ConclusionsThese consensus statements provide further guidance on controversial topics in advanced and variant bladder cancer management until a time when further evidence is available to guide our approach.Patient summaryThis report summarises findings from an international, multistakeholder project organised by the EAU and ESMO. In this project, a steering committee identified areas of bladder cancer management where there is currently no good-quality evidence to guide treatment decisions. From this, they developed a series of proposed statements, 71 of which achieved consensus by a large group of experts in the field of...
Source: European Urology - Category: Urology & Nephrology Source Type: research
Is there any difference in sensitivity to kidney function between men and women? Paterson et  al. have focused on sex differences in chronic kidney disease. Surprisingly, their experimental results show that only one microRNA, miR-146b-5p, affected the susceptibility of renocardiac pathology. They generated miR-146b knockout rats and found that miR-146b−/− females developed exacerbated renal hypertrophy and fibrosis and had less cardiac remodeling. Although miR-146b-5p has been reported to be upregulated in various types of cancers, this article reveals the novel role of miR-146b in the kidney.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research
The objective of this study is to assess information, motivation, and behavioral skills associated with willingness to receive an HPV test instead of a Pap test among women. The sample included U.S. 812 women, ages 30 to 65 years. Participants completed an online survey in 2018. The Information, Motivation, and Behavioral Skills (IMB) model was used to measure predictors of willingness for HPV testing. The outcome variables were willingness to receive the HPV test instead of the Pap test, with and without time interval details. Logistic regression modeling was used with SAS 9.4. Over half of the sample (55%) were willing...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 20 November 2019Source: European Journal of Surgical OncologyAuthor(s): Isabel T. Rubio, Michalis Kontos, M.J. Vrancken-Peeters, Roman Rouzier, Anita Rohini, Viviana Galimberti, Niels Kroman, Carmela Caballero, Shinji Ohno, BIG Task Force Surgical Trials
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Conclusions: Our findings suggest that some subsets of XPD patients may be at risk of radiosensitivity reactions and treatment with statins and bisphosphonates may be an interesting approach of radioprotection countermeasure. Different mechanistic models were discussed to better understand the potential specificity of the p.[Arg683Trp];[Arg616Pro] XPD mutations . PMID: 31738647 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Conclusions: In this review, we examine the role of flavonoids as potential radiosensitizers, review the underlying molecular mechanisms and discuss their potential usefulness in improving cancer radiotherapy. It is emphasized that obtaining a deeper insight into the molecular mechanisms underlying the combined action of flavonoids and ionizing radiation may provide new directions for radiobiological research applicable to the much needed enhanced selective tumor cytotoxicity to treatment agents. PMID: 31738629 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Authors: Li X, Teng S, Zhang Y, Zhang W, Zhang X, Xu K, Yao H, Yao J, Wang H, Liang X, Hu Z Abstract [This corrects the article DOI: 10.18632/oncotarget.16789.]. PMID: 31741718 [PubMed - in process]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
It’s no secret that air pollution isn’t good for your health. In particular, exposure to the byproducts of burning the fuel that powers most of our motor vehicles has been linked to higher risk of lung cancer, respiratory infections, stroke and heart disease, as well as an increased risk of death from these conditions. A new study now adds another worrisome pollution-related risk: eye disease. Dr. Suh-Hang Hank Juo, from the center for myopia and eye disease at China Medical University in Taiwan, and his colleagues documented for the first time in a large population that exposure to two common air pollutants&md...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized health macular degeneration Pollution Source Type: news
Abstract Extensive research during the past three decades has demonstrated the mechanisms by which an imbalance in the redox status of prooxidant/antioxidant reactions in cells with advantage of prooxidant reactions (oxidative stress, OS) can cause peroxidation of nucleic acids, bases, lipids, proteins and carbohydrates, thus resulting in their damage. These actions result in stimulation of signal transduction pathways and activation of transcription factors that can lead to chronic inflammation and cause tissue dysfunction. The most important oxidants are reactive oxygen species (ROS) and reactive nitrogen specie...
Source: Mini Reviews in Medicinal Chemistry - Category: Chemistry Authors: Tags: Mini Rev Med Chem Source Type: research
When kids pack for summer camp, sunglasses may not always top the supply list. But I made them a priority for my 12-year-old son Carson, who just started rowing camp in Florida, for two reasons: Our eyes are most vulnerable to the sun’s ultraviolet rays in our teens, 20s, and 30s, although the damage usually doesn’t show up until later in life. The sun’s rays are especially intense near reflective surfaces. “If you spend time near the water, the beach, or snow, the sunlight bounces off of those surfaces and right into the eyes,” Dr. Louis Pasquale told me. He’s an ophthalmologist at Ha...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Eye Health sunglasses Source Type: news
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