Therapeutic Aptamers: Evolving to Find Their Clinical Niche.

CONCLUSION: In this manuscript, we hope the reader appreciates that the success of aptamers becoming a class of drugs is less about nucleic acid biochemistry and more about target validation and overall drug chemistry.
PMID: 31573879 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - September 30, 2019 Category: Chemistry Authors: Nimjee SM, Sullenger BA Tags: Curr Med Chem Source Type: research