P.281Neurodevelopmental, behavioral and emotional features of Becker muscular dystrophy

Becker muscular dystrophy (BMD) results in a decrease of dystrophin with potential implications for cognitive and psychiatric complications. To better understand these concerns, we conducted a retrospective study of the neuropsychological symptoms and respective pharmacotherapies of 74 BMD patients. Eight (10.8%) patients exhibited autistic features, 26 (35.1%) exhibited inattention/hyperactivity, 23 (31.1%) had learning difficulties, 27 (36.5%) had language delays, 9 (12.2%) had global intellectual delays, 4 (5.4%) had features of tics or Tourette's, 27 (36.5%) had emotion dysregulation, 14 (18.9%) had obsessive-compulsive tendencies, 15 (20.3%) had anxiety, and 4 (5.4%) had depressed mood.

Source: Neuromuscular Disorders - September 30, 2019 Category: Neurology Authors: J. Lambert, A. Darmahkasih, P. Horn, I. Rybalsky, C. Tian, K. Shellenbarger, B. Wong Source Type: research