Malignant acanthosis nigricans associated with cholangiocarcinoma.
CONCLUSION: AN should be considered as cutaneous sign either of malignancy or endocrinopathy and therefore requires further investigations. The existence of extensive lesions, pruritus, tripe palms syndrome, florid cutaneous papillomatosis or mucous lesions, associated to an AN is a sign of malignancy should be investigated urgently the early diagnosis of which can lead to a better prognosis. PMID: 31564378 [PubMed - as supplied by publisher]
We present two cases which are specific for unusual location of Burkitt lymphoma in the colon and stomach, in immunocompetent patients with negative Epstein-Barr virus tests. Also, one of the patients presented is one of the oldest ever reported with abdominal Burkitt lymphoma, while the other patient is an example of diagnostic difficulties in distinguishing Burkitt lymphoma from similar lymphomas. Due to the rapidly growing tumors and urgent need for cytoreductive surgery, it is crucial to consider the diagnosis of Burkitt lymphoma even in atypical localizations or absence of the common risk factors associated with Burki...
Authors: Topolovec Z, Horvat T, Vidosavljević D, Šijanović S, Müller-Vranješ A, Ugljarević M, Milojković D, Topolovec S Abstract The aim of this retrospective study was to present the impact of successful optimal cytoreductive therapy on the overall prognosis of ovarian cancer treatment. Several factors were analyzed, including clinical (stage, age and parity), histopathologic/cytological (histologic type and grade of tumors, cytological findings of ascites or peritoneal washout), and therapeutic (surgery performed with the degree of cytoreduction, adjuvant chemotherapy and response to therap...
Authors: Iorga RA, Bratu OG, Marcu RD, Constantin T, Mischianu DLD, Socea B, Gaman MA, Diaconu CC Abstract Patients with cancer-associated venous thromboembolism (VTE) represent a real challenge in clinical practice. Patients with cancer have a greater risk both of VTE and bleeding. There are only a few studies regarding the therapeutic approach of VTE in patients with cancer, especially after cancer surgery, and on thromboprophylaxis during chemotherapy. Many of the anticoagulation therapy recommendations for cancer patients are extrapolated from trials that are not conducted in cancer cohorts. It is essential to ...
ConclusionTargeted axillary dissection is a feasible technique following excellent response to NACT in selected patients with limited volume ALN metastasis, at diagnosis. The identification of the positive ALN during surgery is vital and the IR can be improved by clipping the node prior to NACT and wire guided localisation at the time of surgery.
This study aims to analyse the outcomes and related prognostic factors of IRE for Asian patients with LAPC.Materials and methodsFrom 2012 to 2017, this prospective trial for using IRE through surgical approaches for LAPC was conducted in 11 medical centres in Asia. All related and treatment outcomes were analysed from a prospective database.ResultsSeventy-four patients were enrolled. Thirty complications occurred in thirteen (17.6%) patients without mortality. The electrode placement direction (anteroposterior vs. craniocaudal, HR = 14.2, p
Conditions: Esophageal Adenocarcinoma; Gastric Adenocarcinoma Intervention: Other: ChemoFit exercise prehabilitation intervention Sponsors: Newcastle-upon-Tyne Hospitals NHS Trust; Newcastle University Recruiting
Condition: Carcinoma, Non-Small-Cell Lung Interventions: Drug: Atezolizumab; Drug: Placebo; Drug: Bevacizumab; Drug: Paclitaxel; Drug: Pemetrexed; Drug: Carboplatin Sponsor: Hoffmann-La Roche Not yet recruiting
Condition: Neoplasms Intervention: Drug: Fluoropyrimidine (capecitabine or 5-fluorouracil) Sponsors: The Netherlands Cancer Institute; Leiden University Medical Center Not yet recruiting
This is a common scenario.1 The goal: maximize freedom from progression but minimize late risks. For a young woman, the main potential late risks secondary to radiation are breast cancer and cardiovascular disease. The main potential late risks from the escalation of chemotherapy are secondary myelodysplastic syndrome and infertility.