Clinical value of genetic analysis in prenatal diagnosis of short femur

ConclusionsCMA yielded a higher detection value than karyotyping in fetuses with other abnormalities or a FL 2 –4 SDs below the GA mean during the second trimester. Gene sequencing should be performed when FL is>4 SDs below the mean.

Source: Molecular Genetics & Genomic Medicine - September 29, 2019 Category: Genetics & Stem Cells Authors: Jialiu Liu, Linhuan Huang, Zhiming He, Shaobin Lin, Ye Wang, Yanmin Luo Tags: ORIGINAL ARTICLE Source Type: research