Sternal Reconstruction with Non-Rigid Biologic Mesh Overlay

We present the case of a large sternal defect after chondrosarcoma resection reconstructed with porcine acellular dermal matrix and soft tissue flaps, without rigid component, with excellent patient outcome through 2 years of follow-up.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

Related Links:

Conditions:   Chondrosarcoma;   Chondrosarcoma, Grade 2;   Chondrosarcoma, Grade 3;   IDH1 Gene Mutation Intervention:   Drug: AG-120 Sponsors:   Memorial Sloan Kettering Cancer Center;   Agios Pharmaceuticals, Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: February 2020Source: Journal of Bone Oncology, Volume 20Author(s): Iseulys Richert, Anne Gomez-Brouchet, Corinne Bouvier, Gonzague Du Bouexic De Pinieux, Marie Karanian, Jean-Yves Blay, Aurélie DutourAbstractSurvival rate for Chondrosarcoma (CHS) is at a standstill, more effective treatments are urgently needed. Consequently, a better understanding of CHS biology and its immune environment is crucial to identify new prognostic factors and therapeutic targets.Here, we exhaustively describe the immune landscape of conventional and dedifferentiated CHS. Using IHC and molecular analyses (RT-qPCR), we m...
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSION: Therefore, apart from probable anti-cancerous effect of rTC-1 on C26-A and SW1353 cell lines, this peptide may be able to mimic the anti-cancerous pathway of IL-8. PMID: 32072885 [PubMed - as supplied by publisher]
Source: Protein and Peptide Letters - Category: Biochemistry Authors: Tags: Protein Pept Lett Source Type: research
Authors: Collaud S, Stork T, Valdivia D, Tokuishi K, Aigner C PMID: 32055421 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Authors: Sandri A, Donati G, Blanc CD, Nigra VA, Gagliasso M, Barmasse R Abstract Chest wall tumours are heterogeneous neoplasms, either primary or metastatic, with a malignancy rate of 50%. Surgical resection is one of the mainstays of the treatment, however, chest wall resections can be particularly challenging depending onto the resection size, site and patient habitus. The surgical strategy should be carefully analysed preoperatively, keeping in mind the need of an oncological radical resection (R0) in accordance to the reconstruction principles elicited by le Roux and Sherma since 1983, which include restoring...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
Conditions:   Efficacy;   Toxicity, Drug Intervention:   Drug: Apatinib Mesylate Sponsor:   Peking University People's Hospital Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Cardiovascular & Thoracic Surgery | Chondrosarcoma | Dermatology