Force-induced recruitment of cten along keratin network in epithelial cells [Cell Biology]

The cytoskeleton provides structural integrity to cells and serves as a key component in mechanotransduction. Tensins are thought to provide a force-bearing linkage between integrins and the actin cytoskeleton; yet, direct evidence of tensin’s role in mechanotransduction is lacking. We here report that local force application to epithelial cells using...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Brief Reports Biological Sciences Source Type: research