Monomeric structure of an active form of bovine cytochrome c oxidase [Biophysics and Computational Biology]

Cytochrome c oxidase (CcO), a membrane enzyme in the respiratory chain, catalyzes oxygen reduction by coupling electron and proton transfer through the enzyme with a proton pump across the membrane. In all crystals reported to date, bovine CcO exists as a dimer with the same intermonomer contacts, whereas CcOs and...

Source: Proceedings of the National Academy of Sciences - September 30, 2019 Category: Science Authors: Kyoko Shinzawa-Itoh, Takashi Sugimura, Tomonori Misaki, Yoshiki Tadehara, Shogo Yamamoto, Makoto Hanada, Naomine Yano, Tetsuya Nakagawa, Shigefumi Uene, Takara Yamada, Hiroshi Aoyama, Eiki Yamashita, Tomitake Tsukihara, Shinya Yoshikawa, Kazumasa Muramoto Tags: Biological Sciences Source Type: research