Redox-dependent gating of VDAC by mitoNEET [Biophysics and Computational Biology]
MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson’s diseases. In healthy cells, mitoNEET receives its clusters from the mitochondrion and transfers them to...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Colin H. Lipper, Jason T. Stofleth, Fang Bai, Yang–Sung Sohn, Susmita Roy, Ron Mittler, Rachel Nechushtai, Jose N. Onuchic, Patricia A. Jennings Tags: Biological Sciences Source Type: research
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