Blue Toes: An Unusual and Mysterious Presentation of Fibromuscular Dysplasia

We report a case of a female patient with rapidly advancing blue discoloration of her feet. Peripheral artery disease (PAD) and thrombosis were quickly ruled out. Eventually, she required transmetatarsal amputation for gangrene. Pathologic analysis confirmed the unexpected diagnosis of fibromuscular dysplasia (FMD), an arterial disease that most frequently causes renal and carotid artery stenosis. Common symptoms include secondary hypertension refractory to antihypertensives, dizziness and pulsatile tinnitus, and abdominal pain due to mesenteric artery involvement.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Letter to the editor Source Type: research