Accelerated cell turnover 48 h after intestinal ischemia is NOTCH independent

ConclusionsForty-eight hours following intestinal IR in rats, accelerated cell turnover was associated by inhibited Notch signaling pathway. Intestinal stem cells differentiation toward secretory progenitors rather than differentiation toward absorptive cells is important at this phase of intestinal recovery.

http://link.springer.com/10.1007/s00383-019-04569-z

Source: Pediatric Surgery International - September 30, 2019 Category: Surgery Source Type: research