3-Dimensional regional and global strain abnormalities in hypertrophic cardiomyopathy

This study evaluated 3D principal and conventional strain characteristics of non-enhanced myocardium in patients with HCM. 3D principal and conventional strain analysis was conducted in 51 HCM patients and 38 healthy controls. Principal strain was reduced within the non-enhanced myocardium of HCM as compared with controls (maximum principal: 51.5 ± 23.7 vs. 75.1 ± 21.4%, P
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research

Related Links:

The "athlete's heart" features in amateur male marathon runners. Cardiol J. 2020 Jan 07;: Authors: Lewicka-Potocka Z, Dąbrowska-Kugacka A, Lewicka E, Kaleta AM, Dorniak K, Daniłowicz-Szymanowicz L, Fijałkowski M, Nabiałek-Trojanowska I, Ratkowski W, Potocki W, Raczak G Abstract BACKGROUND: Training on a professional level can lead to cardiac structural adaptations called the "athlete's heart". As marathon participation requires intense physical preparation, the question arises whether the features of "athlete's heart" can also develop in recreational runners. MET...
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
AbstractAs highly sensitive and specific markers of myocardial damage, cardiac troponins were demonstrated to correlate with clinical parameters of patients with hypertrophic cardiomyopathy. However, the relationship between cardiac troponins and presence of non-sustained ventricular tachycardia (NSVT) in hypertrophic cardiomyopathy remains unclear. The aim of our study was to explore the association between serum cardiac troponin I (cTNI) and presence of NSVT in patients with hypertrophic obstructive cardiomyopathy (HOCM). A total of 309 HOCM patients were enrolled in our study. All participants underwent clinical evaluat...
Source: Heart and Vessels - Category: Cardiology Source Type: research
ConclusionMachine learning-based texture analysis of late gadolinium-chelate enhancement-positive areas is a promising tool for the classification of hypertrophic cardiomyopathy patients with and without VT.
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
In this study, p
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
In this study, p
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
AbstractWe aim to validate echocardiographic left ventricular (LV) mass (echoLVM) in sixty-one patients with hypertrophic cardiomyopathy (HCM), using cardiac magnetic resonance measures (cmrLVM) as gold standard. cmrLVM was calculated using LV short-axis images, from base to apex, whereas echoLVM by LV epicardial minus LV endocardial volumes in 4 and 2 chamber views, using Simpson disk summation; trabeculae and papillary muscle were excluded in both cmrLVM and echoLVM. cmrLVM and echoLVM were not different by pairedt test (145  ± 66 vs 147 ± 61;p = 0.240), and their c...
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research
AbstractLeft ventricular papillary muscles are small myocardial structures that play an important role in the functioning of mitral valve and left ventricle. Typically, there are two groups of papillary muscles, namely the anterolateral and the posteromedial groups. Cardiovascular magnetic resonance (CMR) is a valuable imaging modality in the evaluation of papillary muscles, providing both morphological and functional information. There is a remarkably wide variation in the morphology of papillary muscles. These  variations can be asymptomatic or associated with symptoms related to LV outflow tract obstruction, often ...
Source: Insights into Imaging - Category: Radiology Source Type: research
Conclusion: in this study, the frequency of mutation in the GLA gene in patients with HCM was 6.7%. A novel mutation in exon 6 of the GLA gene, c.967C>A (p.Pro323Thr), was identified. Patients with HCM may have GLA mutations and FD should be ruled out. Plasma (lyso-Gb3) levels do not seem to be sufficient to attain a diagnosis and organ biopsy should be considered.Resumo Fundamento: A doen ça de Fabry (DF) é uma doença de armazenamento lisossômico ligada ao cromossomo X, devido a mutações no gene da alfa galactosidase A (GLA), levando a deficiência enzimática de alfa...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Conclusion: in this study, the frequency of mutation in the GLA gene in patients with HCM was 6.7%. A novel mutation in exon 6 of the GLA gene, c.967C>A (p.Pro323Thr), was identified. Patients with HCM may have GLA mutations and FD should be ruled out. Plasma (lyso-Gb3) levels do not seem to be sufficient to attain a diagnosis and organ biopsy should be considered.Resumo Fundamento: A doen ça de Fabry (DF) é uma doença de armazenamento lisossômico ligada ao cromossomo X, devido a mutações no gene da alfa galactosidase A (GLA), levando a deficiência enzimática de alfa...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Long axis strain (LAS) is a parameter derived from standard cardiovascular magnetic resonance imaging. However, the prognostic value of biventricular LAS in hypertrophic cardiomyopathy (HCM) is unknown.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
More News: Cardiology | Cardiomyopathy | Cardiovascular | Heart | Hypertrophic Cardiomyopathy | MRI Scan | Radiology | Study