32PDelineating the mechanisms of alpha 1-3 fucosyltransferase FUT11 in ovarian cancer

ConclusionsFUT11 promotes invasion and migration of ovarian cancer through regulation of the TGF- β 1-induced EMT process. FUT11 affects the response to TGF-β 1 by regulation of the expression level of R-Smads and Co-Smad, as well as their translocation from cytoplasm to nucleus.Legal entity responsible for the studyBeijing Obstetrics and Gynecology Hospital, Capital Medical University.FundingThe National Natural Science Foundation of China (81502353& 81672838), Beijing Municipal Science& Technology Commission (No. Z181100001718193), and Beijing Obstetrics and Gynecology Hospital, Capital Medical University (FCYY201713).DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research