419PVenous thromboembolism and intracranial hemorrhage in patients with high-grade glioma

ConclusionsAccording to our data, ICH occurred in nearly 20% anticoagulated patients with HGG, as described in literature, and did not correlate with poorer prognosis. High ECOG performance status was an independent risk factor for ICH. Further effort towards better prediction models for VTE and ICH in HGG is warranted.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research

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Authors: Gold PA, Garbarino L, Sodhi N, Barrack R, Springer BD, Mont MA Abstract The demographics of total knee arthroplasty (TKA) patients are changing. Individuals are more active, younger, and more obese. These changing demographics and a higher demand for longevity creates a new challenge for reliable and long-term implant fixation. Historically, cemented fixation has remained the gold standard, as cementless design and techniques from the 1980s and 1990s did not obtain long-term positive outcomes due to a failure of ingrowth onto the implants. Advances in the modern-day cementless TKA designs appear to have ov...
Source: Surgical Technology International - Category: Surgery Tags: Surg Technol Int Source Type: research
Conclusions: Carrying a load on the head leads to accelerated degenerative changes, which involve the upper cervical spine more than the lower cervical spine and predisposes it to injury at a lower threshold. Thus, alternative methods of carrying loads should be proposed. PMID: 32213796 [PubMed - as supplied by publisher]
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Authors: Rudy HL, Cho W, Oster BA, Tarpada SP, Moran-Atkin E Abstract Study Design: Retrospective cohort study. Purpose: To determine the effects of massive weight loss on perioperative complications after lumbar fusion surgery (LFS). Overview of Literature: Patients who are obese are more likely to experience low back pain, which would require LFS. Nonetheless, they have a higher risk of perioperative complication development compared with individuals who are not obese. Methods: Patients who underwent LFS at hospitals that participated in the National Surgical Quality Improvement Program database withi...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Authors: Kaliya-Perumal AK, Soh TLT, Tan M, Oh JY Abstract Study Design: Retrospective radiological analysis. Purpose: To analyze the factors influencing early disc height loss following lateral lumbar interbody fusion (LLIF). Overview of Literature: Postoperative disc height loss can occur naturally as a result of mechanical loading. This phenomenon is enabled by the yielding of the polyaxial screw heads and settling of the cage to the endplates. When coupled with cage subsidence, there can be significant reduction in the foraminal space which ultimately compromises the indirect decompression achieved by L...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
Publication date: Available online 27 March 2020Source: American Journal of Preventive MedicineAuthor(s): Andrew Stokes, Dielle J. Lundberg, Katherine Hempstead, Kaitlyn M. Berry, Joshua F. Baker, Samuel H. Preston
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Authors: Li W, Zhou Y, Shang C, Sang H, Zhu H Abstract Background: Proton pump inhibitor (PPI) and other acid-suppressing drugs are widely used in the treatment of gastrointestinal ulcer, upper gastrointestinal bleeding, gastritis, and gastric cancer (GC). About 80% of GC patients receive acid suppression treatment. PPI suppresses the production of gastric acid by inhibiting the function of H+/K+-ATPase in gastric parietal cells and raises the pH value to achieve therapeutic purposes. Some studies have found that PPI had a certain antitumor effect in the proliferation and apoptosis of tumor cells. But the effects o...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
We present an up-to-date systematic review of the current literature regarding the safety in artificial and natural sweeteners use as a means of weight loss or diabetes control.Expert opinion: Natural sweeteners have not been associated directly with NAFLD, and on the contrary, some, such as stevia, and trehalose, may have a protective effect. Rare sugars and polyols can be used safely and have significant benefits that include anti-oxidant effect and optimal glycemic control. Artificial sweeteners, due to their effect on NAFLD development and insulin resistance, are not indicated in patients with obesity or diabetes. Furt...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
This study shows that ECE is a suitable dietary supplement candidate for the prevention or treatment of obesity or obesity-associated diseases, especially inflammation-related diseases. PMID: 32215011 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Publication date: May 2020Source: Journal of Functional Foods, Volume 68Author(s): Pinggui Wang, Xiang Gao, Yan Li, Shanglong Wang, Jia Yu, Yuxi Wei
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Serious Complication of Anticoagulation in Vessel Thrombosis-associated Behçet Disease. Intern Med. 2020 Mar 26;: Authors: Ouchi K, Narui R, Sakuma T, Ojiri H Abstract Anticoagulation in venous thrombosis associated with Behçet disease (BD) is controversial. We herein report a 47-year-old woman with vessel thrombosis and pulmonary artery aneurysm (PAA) associated with BD who died of massive hemoptysis under oral anticoagulant. Although she was initially diagnosed with oral contraceptive-induced venous thromboembolism, a subsequent investigation led to a diagnosis of BD. Follow-up computed...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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