Trends in Stroke Incidence Rates in Older US Adults

This cohort study evaluates whether stroke incidence declined among older adults from 1987 to 2011 vs 2011 to 2017 in the Atherosclerosis Risk in Communities study.
Source: JAMA Neurology - Category: Neurology Source Type: research

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Publication date: Available online 14 December 2019Source: NeuroscienceAuthor(s): Ahmad Serhan, Joeri L. Aerts, EWGM Boddeke, Ron KooijmanAbstractWe and others have shown that insulin-like growth factor-1 (IGF-1) is neuroprotective when administered systemically shortly following stroke. In the current study, we addressed the hypothesis that microglia mediate neuroprotection by IGF-1 following ischemic stroke. Furthermore, we investigated whether IGF-1 modulates pro- and anti-inflammatory mediators in ischemic brain with a special reference to microglia. Ischemic stroke was induced in normal conscious Wistar rats by infusi...
Source: Neuroscience - Category: Neuroscience Source Type: research
ConclusionsThere was no significant aortic annular dilatation in selected patients undergoing remodelling VSRR. Our data does not support routine use of annuloplasty in patients with annular diameter ≤25mm.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
AbstractPurpose of reviewHyperlipidemia is a key therapeutic target for stroke risk modification. The goal of this review is to highlight available treatment options and review their efficacy in the setting of general cardiovascular disease and after most subtypes of ischemic stroke and hemorrhagic stroke.Recent findingsStatins remain first-line in the management of hyperlipidemia to prevent stroke. In recent trials of patients with pre-existing atherosclerotic vascular disease, new agents, most notably PCSK9 inhibitors and ezetimibe, added additional stroke risk reduction when combined with statins.SummaryRisk of stroke c...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
Myiasis is a disease caused by the invasion of tissues by the larvae of flies. Herein, we present 2 cases of this disease. Case 1: a 47-year-old male patient with diabetes mellitus, hypertension, malnutrition, and mental disorders was hospitalized for sequelae of stroke. The intraoral examination revealed poor hygiene and the presence of an ulcerated lesion with a whitish border in the left upper lip mucosa showing larvae with wriggling movement. Case 2: an 11-year-old male patient diagnosed with cerebral palsy and West syndrome.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
A 51-year-old white female patient hospitalized in the intensive care unit because of acute ischemic stroke who needed tracheostomy and vasoactive drugs in high dosage evolved with aspiration pneumonia and septic shock. At 30 days of hospitalization, intraoral examination revealed multiple superficial ulcers on the lips, buccal mucosa, tongue, and mouth floor, circumscribed by erythematous halo and covered by pseudomembrane with severe pain symptomatology and evolution of 15 days. Concomitantly, the patient presented bilateral conjunctivitis with erythema in the sclera and periocular region.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
This study shows that CA are released from periventricular and subpial regions to the cerebrospinal fluid and are present in the cervical lymph nodes, into which cerebrospinal fluid drains through the meningeal lymphatic system. We also show that CA can be phagocytosed by macrophages. We conclude that CA can act as containers that remove waste products from the brain and may be involved in a mechanism that cleans the brain. Moreover, we postulate that CA may contribute in some autoimmune brain diseases, exporting brain substances that interact with the immune system, and hypothesize that CA may contain brain markers that m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study focused on cognitive motor learning in relation to hand function of stroke survivors. MATERIAL AND METHODS We enrolled 30 subjects with cognitive and hand function disorders. The participants in each group were inpatients at a hospital in Korea and had undergone neurorehabilitation training (60 min). Groups 1 and 3 had tDCS applied for 20 min, while group 2 received sham tDCS for the same duration. Afterwards, groups 1 and 2 played Nintendo games for 20 min, but group 3 did not. The total intervention period was 40 min/day, 2 days/week, for 8 weeks. The cognitive and hand function of the subjects were assessed u...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
A REVOLUTIONARY heart implant that reduces the risk of deadly strokes by up to 70 per cent has been launched.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Thank you for thoughtful comments. I agree with your comment that the possibility of bias exists from combined axillary artery (AA) cannulation. We carried out an analysis comparison outcome of pure AA and non-AA groups. Pure AA (n  = 177) and non-AA (n = 159) groups were reviewed. Results revealed that the AA group showed a lower rate in early stroke (2.8% vs 8.2%, P = .03), as well as lower trends in hospital (5.5% vs 10.1%, P = .09) and 30-day mortality rate (4.5% vs 9.4%, P = .08). In matching data (pairs = 87) , the AA group also showed a lower rate in early ...
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Adult: Aorta: Letter to the Editor Source Type: research
Authors: Kim JW, Huh U, Song S, Sung SM, Hong JM, Cho A Abstract Background: The surgical strategies for carotid endarterectomy (CEA) vary in terms of the anesthesia method, neurological monitoring, shunt usage, and closure technique, and no gold-standard procedure has been established yet. We aimed to analyze the feasibility and benefits of CEA under regional anesthesia (RA) and CEA under general anesthesia (GA). Methods: Between June 2012 and December 2017, 65 patients who had undergone CEA were enrolled, and their medical records were prospectively collected and retrospectively reviewed. A total of 35 patien...
Source: Korean Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Korean J Thorac Cardiovasc Surg Source Type: research
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