The safety of electronic prescribing: manifestations, mechanisms, and rates of system-related errors associated with two commercial systems in hospitals.

CONCLUSIONS: System-related errors are frequent, yet few are detected. e-PS require new tasks of prescribers, creating additional cognitive load and error opportunities. Dual classification, by manifestation and mechanism, allowed identification of design features which increase risk and potential solutions. e-PS designs with fewer drop-down menu selections may reduce error risk. PMID: 23721982 [PubMed - as supplied by publisher]
Source: Journal of the American Medical Informatics Association - Category: Information Technology Authors: Tags: J Am Med Inform Assoc Source Type: research

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Publication date: Available online 21 January 2020Source: Enzyme and Microbial TechnologyAuthor(s): Hyunjun Choe, Minsun Cha, Jon D. StewartAbstractSerine palmitoyltransferase (SPTase), the first enzyme of the sphingolipid biosynthesis pathway, produces 3-ketodihydrosphingosine by a Claisen-like condensation / decarboxylation reaction of L-Ser and palmitoyl-CoA (n-C16-CoA). Previous structural analysis of Sphingomonas paucimobilis SPTase (SpSPTase) revealed a dynamic active site loop (RPPATP; amino acids 378 - 383) in which R378 (underlined) forms a salt bridge with the carboxylic acid group of the PLP : L-Ser external ald...
Source: Enzyme and Microbial Technology - Category: Biotechnology Source Type: research
In this study, platinum electrodes were fabricated on the bio-based poly(ethylene terephthalate) (Bio-PET) substrates for the development of flexible electrochemical sensors for the detection of Parkinson's disease biomarkers. Dopamine was detected by voltammetric measurements, displaying a 3.5 × 10−5 mol L−1 to 8.0 × 10−4 mol L−1 linear range with a limit of detection of 5.1 × 10−6 mol L−1. Parkinson's disease protein 7 (PARK7/DJ-1) was successfully detected by electrochemical impedance spectroscopy after elec...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 21 January 2020Source: Biosensors and BioelectronicsAuthor(s): Lourdes Rivas, Samuel Dulay, Sandrine Miserere, Laura Pla, Sergio Berdún Marin, Johanna Parra, Elisenda Eixarch, Eduard Gratacós, Míriam Illa, Mònica Mir, Josep SamitierAbstractOxygen is vital for energy metabolism in mammals and the variability of the concentration is considered a clinical alert for a wide range of metabolic malfunctions in medicine. In this article, we describe the development and application of a micro-needle implantable platinum-based electrochemical sensor for measuring partial...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 20 January 2020Source: Biosensors and BioelectronicsAuthor(s): C. Chluba, K. Siemsen, C. Bechtold, C. Zamponi, C. Selhuber-Unkel, E. Quandt, R. Lima de MirandaAbstractState of the art minimally invasive treatments and diagnostics of neurological and cardiovascular diseases demand for flexible instruments and implants that enable sensing and stimulation of bioelectric signals. Besides medical applications, implantable bioelectronic brain-computer interfaces are envisioned as the next step in communication and data transfer. Conventional microelectrode arrays used for these types of applica...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 20 January 2020Source: Biosensors and BioelectronicsAuthor(s): Takumi Komikawa, Masayoshi Tanaka, Kentaro Yanai, Benjamin R.G. Johnson, Kevin Critchley, Takeshi Onodera, Stephen D. Evans, Kiyoshi Toko, Mina OkochiAbstractA novel peptide-based three-dimensional probe called “peptide matrix,” inspired by the antibody paratope region, was fabricated on a surface plasmon resonance (SPR) sensor chip to enhance the sensitivity of detecting the explosive 2,4,6-trinitrotoluene (TNT). Although peptide aptamer is an attractive candidate for a molecular recognition probe because of its e...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Conclusions: These results suggest a greater predisposition to experience anomalous perceptual states among high dissociative highly suggestible individuals. PMID: 31955650 [PubMed - as supplied by publisher]
Source: Cognitive Neuropsychiatry - Category: Psychiatry Tags: Cogn Neuropsychiatry Source Type: research
One of the largest companies in Dayton is making changes to its executive leadership. Midmark Corp., a Miamisburg-based provider of medical, dental and veterinary healthcare equipment, has named Jon Dill its newest chief financial officer, effective Feb. 3. He will succeed Bob Morris, who plans to assist with the transition until his retirement at the end of March. Dill joins t he company with more than 30 years of experience in the finance industry. He most recently worked as the operating executive…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Journal Name: Journal of Perinatal Medicine Issue: Ahead of print
Source: Journal of Perinatal Medicine - Category: Perinatology & Neonatology Source Type: research
Publication date: Available online 21 January 2020Source: Journal of Molecular Graphics and ModellingAuthor(s): George Baffour Pipim, Ernest Opoku, Richard Tia, Evans AdeiAbstractThe peri-, chemo-, regio-, stereo- and enantio-selectivities of 1,3-dipolar cycloaddition reaction of C,N-disubstituted nitrones with disubstituted 4-methylene-1,3-oxazol-5(4H)-one have been studied using density functional theory (DFT) at the M06–2X/6-311G (d,p) level of theory. The 1,3-dipole preferentially adds chemo-selectively across the olefinic bond in a (3 + 2) fashion forming the corresponding spirocycloadduct. The titled ...
Source: Journal of Molecular Graphics and Modelling - Category: Molecular Biology Source Type: research
[Nyasa Times] League for Change (LC) has asked government to reverse its decision to withdraw support towards subsidising tuition for the Malawi College of Health Sciences (MCHS) students across the country.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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