Specific elimination of coxsackievirus B3 infected cells with a protein engineered toxin-antitoxin system

ConclusionThese findings suggest that the MazEF fusion protein has a strong potential to be developed as an anti-virus therapy following CVB3 infection.
Source: Molecular and Cellular Toxicology - Category: Cytology Source Type: research

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Abstract The Developing Countries Vaccine Manufacturers Network (DCVMN) convened vaccine manufacturing experts and leaders from local and global public health organizations for its 19th Annual General Meeting. Lectures and panel discussions centered on international cooperation for better access to vaccines, and partnerships in areas ranging from vaccine research and process development, to clinical studies, regulatory, supply chain and emergency preparedness and response. Global vaccine market trends and changes that will impact vaccine financing and procurement methods were discussed as well as capital sources, ...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Qiong Liu Picornaviruses are associated with acute and chronic diseases. The clinical manifestations of infections are often mild, but infections may also lead to respiratory symptoms, gastroenteritis, myocarditis, meningitis, hepatitis, and poliomyelitis, with serious impacts on human health and economic losses in animal husbandry. Thus far, research on picornaviruses has mainly focused on structural proteins such as VP1, whereas the non-structural protein 2B, which plays vital roles in the life cycle of the viruses and exhibits a viroporin or viroporin-like activity, has been overlooked. Viroporins are viral proteins...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Polio Interventions:   Biological: dmLT;   Biological: fIPV Sponsor:   University of Vermont Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: True association of the disease withCampylobacter spp. will enable the proportion ofCampylobacter-induced GBS to be better described in South Africa; this can only be done through systematic studies that include bacterial culture and serology together with molecular methodologies.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
Abstract Childhood diarrhea in low-resource settings has been variably linked to linear growth shortfalls. However, the association between etiology-specific diarrhea and growth has not been comprehensively evaluated. We tested diarrheal stools collected from the Performance of Rotavirus and Oral Polio Vaccines in Developing Countries study from 2011-2013 in Dhaka, Bangladesh by quantitative polymerase chain reaction for a broad range of enteropathogens to characterize diarrhea etiology and examine the association between etiology-specific diarrhea and linear growth and systemic inflammation. Pathogen-specific bur...
Source: Am J Epidemiol - Category: Epidemiology Authors: Tags: Am J Epidemiol Source Type: research
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