Uncertainty quantification of parenchymal tracer distribution using random diffusion and convective velocity fields

ConclusionEven when uncertainties are taken into account, we find that diffusion alone is not sufficient to explain transport of tracer deep into the white matter as seen in experimental data. A glymphatic velocity field may increase transport if a large-scale directional structure is included in the glymphatic circulation.

Source: Fluids and Barriers of the CNS - September 29, 2019 Category: Neuroscience Source Type: research