Mediating role of bone marrow lesion, synovitis, pain sensitization, and depressive symptoms on knee pain improvement following substantial weight loss

ConclusionWeight loss ‐induced knee pain improvement is partially mediated by changes in pain sensitization and depressive symptoms, but is independent of MRI changes in BML and synovitis.

Source: Arthritis and Rheumatology - September 27, 2019 Category: Rheumatology Authors: S. Reza Jafarzadeh, Tuhina Neogi, Joshua J. Stefanik, Jing ‐Sheng Li, Ali Guermazi, Caroline M. Apovian, David T. Felson Tags: FULL LENGTH Source Type: research