Forced Physical Training Increases Neuronal Proliferation and Maturation with Their Integration into Normal Circuits in Pilocarpine Induced Status Epilepticus Mice.

In conclusion, PT increases hippocampal neurogenesis through increasing BDNF levels by some pathways other than demethylating BDNF CpGs and causes post SE newly-born neurons to integrate into normal circuits thus resulting in decreased spontaneous recurrent seizures and enhanced spatial memory. PMID: 31560103 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31560103?dopt=Abstract

Source: Neurochemical Research - September 26, 2019 Category: Neuroscience Authors: Iqbal M, Xiao XL, Zafar S, Yang PB, Si KW, Han H, Liu JX, Liu Y Tags: Neurochem Res Source Type: research