Medtronic Announces New Infuse Trial on Heels of NASS Panel

This study has the potential to add to the broader clinical and scientific evidence regarding use of Infuse and may allow surgeons to better understand its safe and effective use in TLIF procedures.”
Source: MDDI - Category: Medical Devices Authors: Tags: Orthopedics Source Type: news

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ConclusionsCardiac allografts deemed high-risk by utilization and survival based methods led to equivalent post-transplant survival as matched recipients with low-risk donors. This study demonstrates that traditionally high-risk donors may have been associated with worst post-transplant survival because of the recipients that utilized them. Therefore, accepting these “high-risk” donor grafts should be considered as a potential approach to reduce waiting list times and mortality while maintaining comparable post-transplant survival.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This article provides an overview of current findings published in the recent five years regarding the relationship between tacrolimus exposure and variation therein and the development of dnDSA.Expert opinion: In this review we describe how combining data on tacrolimus intra-patient variability and mean pre-dose concentration may be an effective tool to identify kidney transplant recipients who are at higher risk of developing dnDSA. PMID: 31721605 [PubMed - as supplied by publisher]
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
Condition:   Burns Intervention:   Biological: Skin allograft Sponsors:   Virginia Commonwealth University;   AlloSource Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: 2019Source: International Review of Neurobiology, Volume 148Author(s): Isabella R. Grifasi, William Andrew Evans, Annie D. Rexha, Lansana W. Sako, S. Alex MarshallAbstractAlcoholism is a highly visible and prevalent issue in the United States. Although binge-drinking is assumed to be a college-age problem, older adults (ages 65 +) consume binge amounts of alcohol and have alcohol use disorders (AUDs). Moreover, individuals with alcohol dependence in their youth often continue to drink as they age. As such, this study tested the hypothesis that the effects of alcohol on hippocampal microglia are exace...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
Ashok Ramasamy, Dharshan Rangaswamy, Mahesha Vankalakunti, Ravindra Prabhu Attur, Shankar Prasad Nagaraju, Indu RaoIndian Journal of Nephrology 2019 29(6):432-434
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research
We present a reproducible although demanding surgical technique to perform a bipolar fresh osteochondral allograft transplantation of the patella and trochlea.
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
Publication date: Available online 13 November 2019Source: Arthroscopy TechniquesAuthor(s): R. Nelson Mead, Robert Benedict, Orr LimpisvastiAbstractAnterior knee pain and patella fracture are 2 potential complications of bone-patellar-bone autograft anterior cruciate ligament reconstruction. Techniques have been developed to minimize the risk of these complications, including filling the defects with autologous bone fragments and augmenting with biologic agents. We have developed a technique that uses a graft collection device to collect the autologous bone graft generated during surgery. This graft augments the larger bon...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
Publication date: Available online 13 November 2019Source: Arthroscopy TechniquesAuthor(s): Burak Altintas, Frank Martetschläger, Erik M. Fritz, Ryan J. Warth, Joshua A. Greenspoon, Travis C. Burns, Nicole L. Anderson, Peter J. MillettAbstractSurgical exposure of the glenoid after previous coracoid process transfer is technically challenging as a result of distorted anatomy, obliterated soft-tissue planes, and adhesive scar tissue, which poses additional risk to adjacent neurovascular structures. The purpose of this article is to present a technique for glenoid exposure following coracoid transfer that involves tenoto...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
ConclusionsOverall and within the subgroups, the return to sport rate after implant-free iliac bone grafting was high, with a high sense of well-being. The number of sport disciplines decreased significantly and more than one-third of the patients changed disciplines, of which 15% percent changed due to shoulder-related causes. The sport level remained equal, and no other parameters changed significantly compared with the time before the onset of restrictive shoulder symptoms.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
ConclusionThis review demonstrates that SCR is a useful treatment modality for patients with irreparable rotator cuff tears. SCR was associated with significantly improved functional outcome scores in all studies. All studies reported a preserved or increased mean AHD. The radiological graft failure rate ranged from 4.2 to 55% and the short duration of follow-up in most studies means that this remains an important concern that requires longer-term evaluation.Level of evidenceIV, systematic review.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
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