One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P ®/Humate P® treatment in von Willebrand disease patients.

CONCLUSION: This population PK model derived from real world data adequately describes FVIII levels following perioperative administration of the FVIII/VWF plasma-derived concentrate (Haemate® P/Humate P®) and will help to facilitate future dosing in VWD patients. PMID: 31557387 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31557387?dopt=Abstract

Source: Thrombosis and Haemostasis - September 25, 2019 Category: Hematology Authors: de Jager NCB, Bukkems LH, Heijdra JM, Hazendonk CHCAM, Fijnvandraat K, Meijer K, Eikenboom J, Laros-van Gorkom BAP, Leebeek FWG, Cnossen MH, Mathôt RAA, OPTI-CLOT group Tags: J Thromb Haemost Source Type: research