Efficacy of microsurgery in combined with topical-PDT in treating recurrent respiratory papillomatosis: compare JORRP with AORRP.

Efficacy of microsurgery in combined with topical-PDT in treating recurrent respiratory papillomatosis: compare JORRP with AORRP. Acta Otolaryngol. 2019 Sep 26;:1-7 Authors: Yang S, Zhou C, Sun B, Wang F, Han Z, Zhang H, Han J, Shen Y, Zhang J Abstract Background: Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat. Objective: To explore the efficacy of microsurgery in combined with Topical-PDT in treating recurrent respiratory papillomatosis. Materials and methods: Fifty patients with RRP were treated with microsurgery in combined with Topical-PDT. Medical document of each patient was retrospectively reviewed. Detailed clinical information, metrics of clinical course, and current results were evaluated. Results: Juvenile onset RRP (JORRP) might experience a more aggressive course than AORRP (adult onset RRP) with higher Derkay score (p 
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Tags: Acta Otolaryngol Source Type: research

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Recurrent respiratory papillomatosis (RRP) is a rare disease caused by the human papilloma virus (HPV) and characterized by recurrent growth of benign papillomas in the upper and lower respiratory tract. The aim of the study was to increase the effectiveness of RRP treatment using the wide spectrum of diagnostic and therapeutic bronchological methods. 29 patients aged from 18 to 72 years old with RRP were included. In three patients - the juvenile form of RRP was diagnosed, in the remaining- the adult. Flexible bronchoscopy with biopsy and histological examination with microscopic staining and immunohistochemistry (Ki67, p...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
ConclusionLaryngeal papillomatosis is the most common benign tumor in children, but it can also occur in adults. Treatment has been revolutionized by progress in endoscopy and antiviral therapy. However, tracheostomy still occupies an important place in our practice.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
DiscussionUtilisation of TORS improved visualisation, dexterity and access. Drawbacks include cost, set up time, requirement for special equipment and advanced training. TORS approach can be considered as an alternative to the usual laryngoscopic technique, especially in cases where difficult anatomy and poor laryngeal exposure is anticipated.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
ConclusionLaryngeal papillomatosis is the most common benign tumor in children, but it can also occur in adults. Treatment has been revolutionized by progress in endoscopy and antiviral therapy. However, tracheostomy still occupies an important place in our practice.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
DiscussionUtilisation of TORS improved visualisation, dexterity and access. Drawbacks include cost, set up time, requirement for special equipment and advanced training. TORS approach can be considered as an alternative to the usual laryngoscopic technique, especially in cases where difficult anatomy and poor laryngeal exposure is anticipated.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Conclusion Laryngeal papillomatosis is the most common benign tumor in children, but it can also occur in adults. Treatment has been revolutionized by progress in endoscopy and antiviral therapy. However, tracheostomy still occupies an important place in our practice.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
LARYNGEAL papillomatosis is a rare condition.1 The image presented is from a 60-yr-old female with a 5-yr history of dysphagia and progressive dyspnea who presented to an outside hospital for pharyngeal biopsy. Intraoperatively, she had complete airway obstruction, an urgent tracheostomy was performed, and she was transferred to our institution for definitive management. See image of intraoperative laryngoscopy demonstrating the exophytic and proliferative growth of laryngeal papillomatosis lesions that contribute to the risk of complete airway obstruction.
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Discussion Utilisation of TORS improved visualisation, dexterity and access. Drawbacks include cost, set up time, requirement for special equipment and advanced training. TORS approach can be considered as an alternative to the usual laryngoscopic technique, especially in cases where difficult anatomy and poor laryngeal exposure is anticipated.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
CONCLUSION: RRP is a rare disease. Treatment requires experience and may be very difficult. The analysis of the course of the disease has shown that the treatment of choice is surgical excision with the CO2 laser combined with the quadrivalent or polyvalent vaccine. Consequent vaccination of both boys and girls has the potential to reduce the occurrence of RRP. PMID: 28840259 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
CONCLUSION: RRP is a rare disease. Treatment requires experience and may be very difficult. The analysis of the course of the disease has shown that the treatment of choice is surgical excision with the CO2 laser combined with the quadrivalent or polyvalent vaccine. Consequent vaccination of both boys and girls has the potential to reduce the occurrence of RRP. PMID: 28710539 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
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