Compliance in schizophrenia spectrum disorders: the role of clinical pharmacist

In this study, our aim was to evaluate whether drug education provided by a clinical pharmacist during discharging period has an effect on compliance. Forty adult patients diagnosed with psychotic disorders were included. A number of scales were used to evaluate the severity of illness, medication adverse effects and compliance. At time of discharge, it was emphasized to patients by a clinical pharmacist that medication compliance was important to prevent exacerbation or hospitalization. Six to eight weeks after discharge, patients were invited to be reevaluated using the same scales as those applied during hospitalization. There was a statistically significant increase in compliance after drug education (P
Source: International Clinical Psychopharmacology - Category: Psychiatry Tags: Original Articles Source Type: research

Related Links:

We report here the derivation of familial iPSC lines from two controls and three ASD patients carrying NRXN1α+/−, using a non-integrating Sendai viral kit. The genotype and karyotype of the resulting iPSCs were validated by whole genome SNP array. All iPSC lines expressed comparable levels of pluripotency markers and could be differentiated into three germ layers.
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Authors: Santarelli V, Marucci C, Collazzoni A, Rossetti MC, Pizziconi G, Pacitti F, Stratta P, Rossi A, Rossi R Abstract The relationship between subjective appraisal of cognitive deficits and symptom severity in schizophrenia is unclear. Insight reportedly affects both factors. Our aim is to further asses the relationship between subjective perception of cognitive deficits, symptom severity and lack of insight as a mediator variable. 109 subjects with schizophrenia were evaluated. Positive and Negative Syndrome Scale (PANSS) was modelled as independent variable, Subjective Scale to Investigate Cognition in Schizo...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
This study examined mental health perceptions held by Chinese immigrant parents of youth. METHODS: Eighteen parents (13 female, 5 male), who identified as having children between the ages of 13 and 21 years, participated in audio-recorded interviews using five vignettes depicting depression with and without a somatic emphasis, schizophrenia with paranoid features, attenuated psychosis syndrome, and social anxiety in youth. Questions about potential causes, likely diagnosis, and health-seeking behaviors in relation to these vignettes were asked. Interviews were analyzed for themes using a deductive-inductive hybrid appr...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Authors: Li W, Yang Y, Hong L, An FR, Ungvari GS, Ng CH, Xiang YT Abstract OBJECTIVE: Aggression is common in patients with schizophrenia and is clinically significant, but its prevalence is inconsistent across studies. This is a meta-analysis of the prevalence of aggression and its associated factors in patients with schizophrenia. METHODS: PubMed, EMBASE, PsycINFO, the Cochrane Library, Medline and Web of Science databases were systematically searched. Studies that reported the prevalence of aggression in patients with schizophrenia using the Modified Overt Aggression Scale (MOAS) were included and analyzed u...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
CONCLUSIONS: Forty-one percent of the respondents did not feel comfortable with clozapine prescription. Major concerns cited included the side effect profile as well as lack of experience and training. The majority of the respondents felt that they would be more comfortable prescribing clozapine if they had the opportunity to train in a clozapine clinic. PMID: 31713078 [PubMed - as supplied by publisher]
Source: The Journal of American Association of Directors of Psychiatric Residency Training - Category: Psychiatry Tags: Acad Psychiatry Source Type: research
DISCUSSION: ED utilization after outpatient hand surgery is low, with postoperative pain being the most common cause of an ED visit at all time points. Nearly 98% of patients presenting to the ED for postoperative pain are subsequently discharged home. LEVEL OF EVIDENCE: Level III, Retrospective Cohort. PMID: 31714419 [PubMed - as supplied by publisher]
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Incorporating genetic data into a clinical tool that predicts whether a person will develop schizophrenia can improve the accuracy of this tool, according to astudy appearing inAJP in Advance.Diana Perkins, M.D., M.P.H., of the University of North Carolina and colleagues assessed whether polygenic risk scores (PRS) could be used as part of a clinical assessment of schizophrenia risk. A PRS reflects how many individual genetic variants associated with schizophrenia a person has; the higher an individual ’s PRS, the greater his or her genetic risk of developing schizophrenia. They looked at health data from 764 young a...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance Diana Perkins DNA genetic data North American Prodrome Longitudinal Study polygenic risk score psychosis schizophrenia Source Type: research
Minimal/non-response to antipsychotic treatment, and persistent positive symptoms despite treatment, are common among patients with schizophrenia. The aim of this study was to characterize a US treatment-resis...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
Patients suffering from schizophrenia spectrum disorders demonstrate various cognitive deficiencies, the most pertinent one being impairment in autobiographical memory. This paper reviews quantitative research...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
Publication date: Available online 12 November 2019Source: Progress in NeurobiologyAuthor(s): Joseph H. Neale, Tatsuo YamamotoAbstractN-Acetylaspartylglutamate (NAAG) is the third most prevalent neurotransmitter in the mammalian nervous system, yet its therapeutic potential is only now being fully recognized. Drugs that inhibit the inactivation of NAAG by glutamate carboxypeptidase II (GCPII) increase its extracellular concentration and its activation of its receptor, mGluR3. These drugs warrant attention, as they are effective in animal models of several clinical disorders including stroke, traumatic brain injury and schi...
Source: Progress in Neurobiology - Category: Neuroscience Source Type: research
More News: Education | Psychiatry | Schizophrenia | Statistics | Study | Universities & Medical Training