Probiotics Prevent Diarrhoea Related To Antibiotic Use

Probiotic supplements have the potential to prevent diarrhoea caused by antibiotics, according to a new Cochrane systematic review. The authors studied Clostridium difficile (C. difficile) infections in patients taking antibiotics and found symptoms of diarrhoea were substantially reduced when patients were also treated with probiotics. Antibiotics disturb the beneficial bacteria that live in the gut and allow other harmful bacteria like C. difficile to take hold. Although some people infected with C. difficile show no symptoms, others suffer diarrhoea or colitis...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

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Authors: Duran G, Cruz R, Simoes AR, Barros F, Balboa E, Giráldez JM, Bernárdez B, Anido U, Candamio S, López-López R, Carracedo Á, Lamas MJ Abstract We studied the predictive value for response and toxicity of functional polymorphisms in genes involved in the oxaliplatin/fluorouracil pathway in colorectal cancer patients. One hundred and twenty-seven (127) patients were treated with curative intended surgery followed by adjuvant chemotherapy with FOLFOX (fluorouracil, leucovorin and oxaliplatin) regimen. The median age was 65.53 (27-80) years (66.9% male, 59.1% rectum). The media...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
ConclusionAfter great improvements in rectal cancer treatment, late gastrointestinal toxicity after radiotherapy is experienced less frequent and less severe; however, it remains a great concern associated with worse quality of life.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Publication date: June 2020Source: The Lancet Global Health, Volume 8, Issue 6Author(s): Gbemisola Allwell-Brown, Laith Hussain-Alkhateeb, Freddy Eric Kitutu, Susanne Strömdahl, Andreas Mårtensson, Emily White Johansson
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Authors: Mateu L, Fernández-Rivas G, Sopena N Abstract Clostridioides difficile is the main cause of healthcare-associated diarrhoea in adults. The incidence of C.difficile infection (CDI) has increased in recent years. The risk of recurrence of CDI is 15%-25% in a first episode and this risk is increased in subsequent episodes. Toxigenic culture and cytotoxicity tests are the reference techniques for the microbiological diagnosis of CDI. These are laborious and slow techniques and therefore they have been replaced in clinical practice by the application of a multi-step algorithm that includes the detection ...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Diarrhoea is one of the major contributors to death among under-five children in Ethiopia. Studies conducted in different countries showed that rural children are more severely affected by diarrhoea than urban...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research
DiscussionThis review will provide a comprehensive examination of a possible association between suboptimal household flooring and increased risk of enteric pathogen infection, highlight gaps for future research in high risk areas, and inform intervention design for future planned studies in Kenya and/or elsewhere in the region.Systematic review registrationPROSPERO registration number: CRD42019156437
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Publication date: Available online 17 May 2020Source: Veterinary ParasitologyAuthor(s): Caroline Jacobson, John WA Larsen, R. Brown Besier, Joan B. Lloyd, Lewis P Kahn
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Authors: Kumar J, Yadav A PMID: 32400302 [PubMed - as supplied by publisher]
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Conclusions: The study suggests that vapreotide may be a choice of drug for wet lab studies to inhibit the infection of SARS-CoV-2. PMID: 32399096 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
ConclusionsThis new CBD formulation demonstrated a favourable safety and tolerability profile in healthy volunteers that was consistent with the profiles reported for other purified CBD products. No severe or serious AEs were observed in this study and there were no safety concerns.Trial RegistrationACTRN12618001424291. Registered August 2018.
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research
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