MACC1 regulates PDL1 expression and tumor immunity through the c ‐Met/AKT/mTOR pathway in gastric cancer cells

ConclusionsFrom these data, we infer that MACC1 regulates PDL1 expression and tumor immunity through the c ‐Met/AKT/mTOR pathway in GC cells and suggest that MACC1 may be a therapeutic target for GC immunotherapy.

Source: Cancer Medicine - September 25, 2019 Category: Cancer & Oncology Authors: Gangling Tong, Boran Cheng, Jingzhang Li, Xuan Wu, Qiaohong Nong, Lirui He, Xi Li, Laiqing Li, Shubin Wang Tags: ORIGINAL RESEARCH Source Type: research