Surgical Treatment of Infective Endocarditis in Pulmonary Position-15 Years Single Centre Experience.

Surgical Treatment of Infective Endocarditis in Pulmonary Position-15 Years Single Centre Experience. Medicina (Kaunas). 2019 Sep 19;55(9): Authors: Liekiene D, Bezuska L, Semeniene P, Cypiene R, Lebetkevicius V, Tarutis V, Barysiene J, Rucinskas K, Sirvydis V Abstract Background and Objectives: Infective endocarditis in the pulmonary position is a rare disease. Isolated pulmonary valve endocarditis is extremely rare. The aim of our study was to assess patients who were treated surgically for pulmonary endocarditis at our institution from January 2003 to December 2017. Materials and Methods: We analyze eight cases of infectious endocarditis in pulmonary position out of 293 patients who were operated for infective endocarditis (2.7%, 8/293). Only two of these eight patients were not related to congenital heart malformation. They were followed for early and late mortality, long-term survival, postoperative morbidity and reoperations. Results: Among six patients suffering from congenital heart disease, four patients underwent corrections of pulmonary valve malformation previously, and their infected grafts were replaced by two allografts and two xenografts. The two other patients had replaced their infected pulmonary valves with allografts. Two non-congenital patients with pulmonary valve endocarditis underwent valve replacement with biological prosthesis. All patients survived the early postoperative course. The mean follow-up time was 9.1 (interquartile r...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research

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Source: Coronary Artery Disease - Category: Cardiology Tags: Risk Factors Source Type: research
Publication date: Available online 9 December 2019Source: Life SciencesAuthor(s): Qi Wei, Yuzhen Tu, Lin Zuo, Jia Zhao, Zhongbao Chang, Yan Zou, Jizhe QiuAbstractAimsAtherosclerosis is a risk factor for coronary heart disease and cerebral infarction. Recent reports show decreased miR-345-3p in apolipoprotein-E deficient mice. Our study aimed to determine the biological activities of miR-345-3p in endothelial cells exposed to oxidized low-density lipoprotein (oxLDL).Main methodsHuman umbilical vein endothelial cells were transfected with miR-345-3p mimic and then exposed to oxLDL. Expression of miR-345-3p was assayed using ...
Source: Life Sciences - Category: Biology Source Type: research
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European guidelines on a form of heart disease are under review, following a Newsnight investigation.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
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Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
Conditions:   Hypertension;   Heart Failure;   Hypertensive Heart Disease;   Diastolic Dysfunction Intervention:   Sponsor:   Karolinska Institutet Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
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