Laminin α4 contributes to airway remodeling and inflammation in asthma.

This study for the first time indicates a prominent role for laminin α4 in ASM function and in inflammation, AHR and remodeling in asthma, whereas the role of laminin α5 is more subtle.
PMID: 31553662 [PubMed - as supplied by publisher]

Source: Am J Physiol Lung Ce... - September 24, 2019 Category: Respiratory Medicine Authors: Prabhala P, Wright DB, Robbe P, Bitter C, Pera T, Ten Hacken NHT, van den Berg M, Timens W, Meurs H, Dekkers BGJ Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research