Palliative Care Triggers for Oncology

I read the ASCO Post when I’m on airplanes.  At least I do, below 10,000 feet… and after I have finished the Sudoku. The ASCO Post is the People magazine of oncology.  The articles are short… typically one page, with lots of pictures consisting mostly of the authors.  It is medical journal lite, with terms and prose simple enough for a layman to both understand and to not fall asleep by the end of the article.  It probably can be best described as Oncology for Dummies. (Also, to give the full extent of its look and feel… there is usually one or two ads attached with that gooey stuff you try to pull off the paper, but the kind that usually snaps back and hits you in the eye.) In any event, the May 1st issue featured an article on access to care. The title suggested it was about patient access to oncologic care, depending on geographic and economic factors. That was a focus, but I’m glad I kept reading to see that it wasn’t the only focus. The last section of the article was titled, “Missed Opportunities for End-of-life Care?”  If I hadn’t kept reading, it definitely would have been a missed opportunity for me. The article summarized a manuscript in the Journal of Oncology Practice authored by Gabrielle B. Rocque, MD and her colleagues. This group analyzed data from their institutions and determined that an unscheduled hospitalization for a patient with advanced cancer, “strongly predic...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Carer Workers Authors: Source Type: blogs

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CONCLUSION: Patients with mCRC receiving cetuximab + FOLFIRI who presented with high plasma HGF levels had significantly worse PFS and OS. Cetuximab resistance induced by HGF was mediated by AKT and ERK activation and overcome by MET inhibition in vitro.PMID:34853888 | DOI:10.1007/s00432-021-03872-4
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Source Type: research
Conclusions: Having a clinical pathway and systematizing palliative care could be important to determine the possibility of at-home deaths for cancer patients in rural clinics in Japan.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Brief Report Source Type: research
ConclusionThe Delphi-consented recommendations for parents and adult children at the end of life provide the first guidance for hands-on dyadic psychosocial support measures for parent –adult child relationships, specifically. The next step could involve the structured implementation of the recommendations, accompanied by scientific research.This study was registered on October 27, 2017, with the German Clinical Trials Register (DRKS00013206).
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionsHome assistance was provided in a high number of patients, with a large proportion needing one or no hospital admissions and 70.1% of them dying at home. Further studies characterizing these patients and the factors which promote early access to palliative care are needed.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
ConclusionThe maximum respiratory rate and mean heart rate measured every minute using a monitor can warn family caregivers and care staff, with the support of palliative care professionals, of imminent death among dying patients at home or other facilities.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
Conclusions: The PRIM rapid transition to remote work was associated with positive perceptions by most members of the clinical, research, and administrative teams. Insight from this survey can serve as a model for future rapid transitions in remote work and merits follow-up studies to prepare us for a postpandemic work environment. Clinical Trial Registration number NCI-2021-01265.PMID:34847735 | DOI:10.1089/jpm.2021.0343
Source: Primary Care - Category: Primary Care Authors: Source Type: research
A 59-year-old man with recurrent rectal cancer and type 2 diabetes mellitus underwent palliative total pelvic exenteration and intraoperative radiotherapy. After surgery, he experienced a pelvic abscess and abdominal-perineal fistula. Profuse exudate contaminated the midline abdominal incision through the abdominal-perineal fistula and delayed healing. Because of a residual tumor and the high cost, negative-pressure wound therapy was not performed. After 76 days of local treatment that involved removing necrotic tissue, controlling inflammation with an antimicrobial silver dressing, absorbing and draining exudate with a hy...
Source: Advances in Skin and Wound Care - Category: Dermatology Tags: CASE REPORT Source Type: research
Journal of Palliative Medicine, Ahead of Print.
Source: Journal of Palliative Medicine - Category: Palliative Care Authors: Source Type: research
Conditions:   Gastrointestinal Cancer;   Lung Cancer;   Advanced Cancer Intervention:   Other: Specialty Palliative Care Sponsors:   Dartmouth-Hitchcock Medical Center;   Dartmouth College Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this commentary, scientists note the paucity of funding for chronic kidney disease research, given the widespread suffering and death caused by this presently incurable condition. This and many other areas of medicine are seen as solved problems by the powers that be simply because there is some form of treatment, even palliative treatment, in widespread use. That the treatment does little and many people die doesn't appear to motivate those who could fund progress. There is no sense of urgency and little sense of need. We might make the same comments in the case of atherosclerosis, a condition many consider to be adequ...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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