Data Sharing: A Cholera Case Study

Source: Wellcome Trust. Published: 11/30/2019. This 27-page study aims to better understand the barriers and enablers for research data sharing during recent epidemics of cholera in Western Africa. It takes into consideration the experiences at a country level from outbreaks in Guinea and C ôte d’Ivoire in 2012 and 2014 respectively, as well as the region’s general experience up until 2018, to gather specific and general lessons learned. The study was also funded by United Kingdom Department of International Development. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news

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This study envisages the characterisation of isolated pathogen from two cholera outbreaks reported in 2018 and 2019 from Bargarh and Rayagada districts of Odisha respectively. Vibrio cholerae O1 were isolated following standard techniques. The different virulent and drug resistant genes were detected by multiplex PCR assays; whereas the ctxB genotypes were characterised through double mismatch amplification mutation (DMAMA) PCR assay. The ctxB genes were further sequenced and pulse-field gel electrophoresis (PFGE) was done on some selected strains. The clinical and water isolates of Haitian variant (HCT) V.cholerae O1 Ogaw...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research
Authors: Ng QX, De Deyn MLZQ, Loke W, Yeo WS Abstract Yemen has been faced with the worst cholera epidemic of modern times, with more than 1 million suspected cases and 3000 deaths at the time of writing. This problem is largely due to the longstanding civil war between pro-government forces and the Houthi armed movement, which has severely damaged already vulnerable sanitation and healthcare facilities and systems in the country. It is further compounded by a dire lack of basic amenities, chronic malnutrition, and unfavourable weather conditions. Another contributory component may be aerial transfer by cholera-inf...
Source: Journal of Preventive Medicine and Public Health - Category: International Medicine & Public Health Tags: J Prev Med Public Health Source Type: research
by Doudou Batumbo Boloweti, Patrick Giraudoux, Catherine Deniel, Emmanuel Garnier, Frederic Mauny, Celestin Mahinda Kasereka, Roger Kizungu, Jean Jacques Muyembe, Didier Bompangue, Gudrun Bornette We hypothesized that Cholera (Vibrio cholerae) that appeared along Lake Kivu in the African Rift in the seventies, might be controlled by volcano-tectonic activity, which, by increasing surface water and groundwater salinity and temperature, may partly rule the water characteristics of Lake Kivu and promoteV.cholerae proliferation. Volcanic activity (assessed weekly by the SO2 flux of Nyiragongo volcano plume over the 2007 &ndas...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Countries around the world have introduced stringent control measures to stop COVID-19 outbreaks growing, but now many find themselves facing the same situation again. From Melbourne to Miami, the relaxation of measures had led to increasing flare-ups, which in some places has already meant reclosing schools, businesses or travel routes. Within the U.S. and among different countries, places with wildly varying public-health policies have experienced wildly diverse outcomes. Most ominously, infections are rising rapidly in many places where they once were falling. So how do countries avoid an indefinite, unsustainable, cycl...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Abstract In the past two centuries, several fatal infectious outbreaks have arisen in Iran. Presented here is a brief historical account of four fatal epidemics including cholera, plague, Spanish influenza of 1918 and smallpox between1796 and 1979. The lessons from these outbreaks could be helpful for better combatting other deadly epidemics including the present-day disastrous COVID-19 pandemic. PMID: 32894975 [PubMed - in process]
Source: Archives of Iranian Medicine - Category: Middle East Health Authors: Tags: Arch Iran Med Source Type: research
by Alexandra Smirnova, Natalie Sterrett, Oscar J. Mujica, C ésar Munayco, Luis Suárez, Cécile Viboud, Gerardo Chowell After being cholera free for over 100 years, Peru experienced an unprecedented epidemic ofVibrio cholerae O1 that began in 1991 and generated multiple waves of disease over several years. We developed a mechanistic transmission model that accounts for seasonal variation in temperature to estimate spatial variability in the basic reproduction number (R0), the initial concentration of vibrios in the environment, and cholera reporting rates. From 1991-1997, cholera spread following a mult...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Left: German Ambassador to Singapore Ulrich Sante and Foreign Minister Vivian Balakrishnan at the official opening of the German European School Singapore on Sept 13, 2018. Dr Sante says he will be leaving Singapore with a heavy heart but also a treasure trove of good memories. PHOTO: GERMAN EUROPEAN SCHOOL SINGAPOREBy Dr. Iftekhar Ahmed ChowdhurySINGAPORE, Jun 15 2020 (IPS-Partners) The departing German envoy in Singapore, Ambassador Ulrich Sante, in a recent published article in the Straits Times shared some of his thoughts with the readership including on the impact on the community of the COVID-19 Pandemic. Among other...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Economy & Trade Health Source Type: news
Devyn Holliday, Research Officer, Economic, Youth &Sustainable Development Directorate   This blog is part of the seminar series on ‘The Economics of COVID-19’.By Devyn HollidayJun 10 2020 (IPS-Partners) When countries shuttered their shops, closed their markets, and cordoned off places of gathering to help ward off the coronavirus, they did so out of immediate concern for the health and wellbeing of their citizens. However, as these measures endure the virus is no longer the sole threat to the health and wellbeing of citizens. People across the globe are facing mounting threats to their wellbeing c...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Economy & Trade Health Labour Source Type: news
Abstract On October 6, 2017, the Zambia Ministry of Health declared a cholera outbreak in Lusaka. By December, 1,462 cases and 38 deaths had occurred (case fatality rate, 2.6%). We conducted a case-control study to identify risk factors and inform interventions. A case was any person with acute watery diarrhea (≥ 3 loose stools in 24 hours) admitted to a cholera treatment center in Lusaka from December 16 to 21, 2017. Controls were neighbors without diarrhea during the same time period. Up to two controls were matched to each case by age-group (1-4, 5-17, and ≥ 18 years) and neighborhood. Surveyors interview...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
Conclusion: The current study identified phage type 27 as the most dominant type and serotype Ogawa was found continuous in circulation throughout the year which has caused recent cholera outbreaks in India during the past years. Phage sensitivity data propose an alternative cost-effective approach to prevent cholera outbreak by therapeutic uses of typing phages irrespective of origin or clonality of the strains.
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
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