Pholidonone, an active stilbene derivative from Pholidota cantonensis, exhibits pro-apoptotic effect via induction of endoplasmic reticulum stress in human gastric cancer.
Conclusion: Pholidonone can trigger ER stress-induced apoptosis through PERK and IRE1α signaling pathways. Pholidonone might be a potential naturally occurring antitumor agent.
PMID: 31548837 [PubMed]
Source: Food and Nutrition Research - Category: Nutrition Authors: Liu L, Wang W, Zhao Z, Hu C, Tao L, Zhang X Tags: Food Nutr Res Source Type: research
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