Tenofovir is a more suitable treatment than entecavir for chronic hepatitis B patients carrying naturally occurring rtM204I mutations.

CONCLUSION: The newly developed LNA-RT-PCR method could detect naturally occurring rtM204I mutations with high-sensitivity. Theses mutations were more frequent in patients with liver fibrosis. Tenofovir is a more suitable treatment than entecavir for CHB patients carrying the naturally occurring rtM204I mutations.
PMID: 31543688 [PubMed - in process]

Source: World Journal of Gastroenterology - September 6, 2019 Category: Gastroenterology Authors: Choe WH, Kim K, Lee SY, Choi YM, Kwon SY, Kim JH, Kim BJ Tags: World J Gastroenterol Source Type: research