Time to First Culture Positivity Among Critically Ill Adults With Methicillin-Resistant Staphylococcus aureus Growth in Respiratory or Blood Cultures.

Conclusion and Relevance: This analysis of a large cohort of critically ill adults receiving empirical vancomycin found that Staphylococcus aureus was present in all but 15% of cases of MRSA-positive respiratory cultures after 48 hours, whereas Gram-positive cocci were identified within 48 hours during nearly all episodes of MRSA bacteremia. These findings may inform the timing of discontinuation of empirical vancomycin among critically ill adults. PMID: 31544471 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31544471?dopt=Abstract

Source: The Annals of Pharmacotherapy - September 21, 2019 Category: Drugs & Pharmacology Authors: Melling PA, Noto MJ, Rice TW, Semler MW, Stollings JL Tags: Ann Pharmacother Source Type: research