Epilepsy drug could help prevent TINNITUS because it reduces 'hyperactivity' of cells in the ear

Researchers from the University of Pittsburgh found that retigabine prevented the chronic and often debilitating hearing condition from developing after exposure to loud noise in mice.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 19 August 2018Source: Epilepsy &BehaviorAuthor(s): Selim R. Benbadis
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
There may be a strong connection between asthma and attention deficit hyperactivity disorder (ADHD) that makes people with one condition more likely to develop the other one, a recent study suggests.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
Authors: Yu J, Shi Z, Su X, Zhou Y, Li B, Wang S, Jia L, Zhao B, Zhu M, Feng X, Yin K, Wang W Abstract Injury of hippocampal neurons in status epilepticus (SE) SD rats kindled by pentylenetetrazol (PTZ) were studied, and the changes of apoptosis neurons, protein expression of Bad and Bcl-2 alone and combined application of phosphatidyl inositol 3-kinase (PI3K) inhibitor LY294002 and recombinant human erythropoietin (rHuEpo) were evaluated for the possible mechanisms of rHuEpo. The SE rats kindled by the PTZ were randomly divided into normal control group [normal saline (NS)], model group (PTZ + NS), rHuEpo treated ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
In conclusion, no significant differences were identified in the cure rate and the mortality rate of patients with CSDH after the two types of surgical treatment. However, the mRS score in the TDC group at 3 months after the operation exhibited a significantly greater improvement compared with that in the BHC group, and the overall LOS in the TDC group was significantly shorter than that in BHC group. Therefore, TDC is superior to BHC in the treatment of CSDH (trial registration no. ChiCTR-INR-16008368). PMID: 30116345 [PubMed]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Russell DeJong: "The most scholarly neurologist in the Academy". J Hist Neurosci. 2018 Jul-Sep;27(3):245-250 Authors: Reich SG Abstract Russell Nelson DeJong (1907-1990) became professor and chair of the Department of Neurology at the University of Michigan in 1950. A prolific author with more than 200 publications, DeJong wrote on virtually all areas of neurology. DeJong's classic monograph, The Neurologic Examination (1950), grew into an encyclopedic volume from lectures he gave to junior and senior medical students; DeJong saw it through four editions. He was one of the founders of the Ame...
Source: Journal of the History of the Neurosciences - Category: Neuroscience Tags: J Hist Neurosci Source Type: research
This study aimed to determine early echocardiographic findings of Left Ventricular (LV) dysfunction using cardiac strain technique in seizure-free children with epilepsy.MethodThe study investigated 60 children with epilepsy who had no seizures in the preceding 6 months, without any known cardiovascular disease and treated with one antiepileptic drug and 60 healthy subjects who underwent clinical evaluation including electrocardiography (ECG), standard echocardiography, tissue Doppler imaging (TDI) and two-dimensional Speckle Tracking Echocardiography (2DSTE).ResultsDespite the normal M-mode values, global longitudinal str...
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 18 August 2018Source: SeizureAuthor(s): E. Fonseca Hernández, M. Olivé Gadea, M. Requena Ruiz, M. Quintana, E. Santamarina Pérez, L. Abraira del Fresno, J. Álvarez Sabín, X. Salas Puig, M. ToledoAbstractPurposeNew-onset seizures (NOS) are a common reason for emergency department (ED) consultations. Decisions regarding treatment and further examinations are made based on the initial evaluation. We aimed to evaluate the reliability of the early syndromic diagnosis in NOS and find predictive factors to establish a consistent early diagnosis based on the sem...
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 18 August 2018Source: Epilepsy &BehaviorAuthor(s): Anne E. Keller, Laura Bradbury, Laura Wang, Ivanna Yau, Elizabeth J. DonnerAbstractObjectiveLimited evidence on the relationship between antiepileptic drug (AED) tapering and the likelihood of a seizure during an Epilepsy Monitoring Unit (EMU) admission is available, and no evidence specific to the pediatric population has been published. Our study sought to determine whether AED tapering leads to increased seizure likelihood in a pediatric EMU setting.MethodsWe performed a retrospective chart review of children admitted to the pediat...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 18 August 2018Source: Epilepsy &BehaviorAuthor(s): Lilach Goldstein, Boris Shihman, Noam Amiel, Felix BenningerAbstractAntiepileptic drugs (AEDs) are commonly prescribed to women of childbearing age. As 0.3%–0.7% of all pregnancies occur in women with epilepsy (WWE), the effect of recurrent seizures and teratogenicity on pregnancy outcome and the fetus have been widely studied. Most of these studies have focused on live births. A significant number of terminated pregnancies in WWE were ignored in past studies, thus reducing the calculated incidence of congenital malformations an...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 18 August 2018Source: Epilepsy &BehaviorAuthor(s): Mamta Bhushan Singh
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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