MiR-21 in Substance P-induced exosomes promotes cell proliferation and migration in human colonic epithelial cells.

CONCLUSIONS: Our results demonstrate that SP/NK-1R signaling regulates exosome biogenesis and induces their miR-21 cargo sorting. Moreover, exosomal miR-21 promotes proliferation and migration of target cells. PMID: 31545921 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - Category: Physiology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research