Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy

Conclusion: Although the number of studies on the clinical use of AO is limited, pilot studies have demonstrated the safety and feasibility of its application as an intraoperative fluorescent dye and as a novel photo- and radio-sensitizator. Further clinical studies are necessary to more definitively assess the clinical benefit AO-based fluorescence guidance, therapy for sarcomas, and to establish feasibility of this new approach for the treatment of other tumor types.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research