Boosting Body's Natural Killers May Be The Way Forward For Fighting Flu

A known difficulty in fighting influenza (flu) is the ability of the flu viruses to mutate and thus evade various medications that were previously found to be effective. Researchers at the Hebrew University of Jerusalem have shown recently that another, more promising, approach is to focus on improving drugs that boost the body's natural flu killer system. Emergence of new influenza strains, such as the recent avian influenza (H5N1) and swine influenza (H1N1 2009), can lead to the emergence of severe pandemics that pose a major threat to the entire world population...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Flu / Cold / SARS Source Type: news

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Avian ocular disease may be primary or a manifestation of systemic disease. Various infectious and noninfectious diseases have been reported to cause ocular pathology. Thorough physical examination and diagnostic testing are necessary to determine a treatment plan.
Source: Veterinary Clinics of North America: Exotic Animal Practice - Category: Veterinary Research Authors: Source Type: research
See something of interest? Please share our postings with colleagues in your institutions! Spotlight Deadline Extended! Apply by November 23 to participate in the 2019 Critical Appraisal Institute for Librarians! – Craving more confidence in leading EBM sessions for medical students? Puzzled on how to guide students about study design and in depth critical appraisal? Frustrated with statistics? This six week online program will develop librarian’s critical appraisal skills via enhanced understanding of research design, biomedical statistics, and clinical reasoning to apply knowledge in teaching target populatio...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
We describe here that pre-exposure with a live virus generated via a A/WSN/1933(H1N1) reverse genetics system resulted in a significant reduction of viral shedding from pigs exposed to either a swine H1N1 virus or a swine H3N2 virus. At 3-day post challenge (DPC), approximately 1 log and 1.5 logs reductions of viral shedding were observed in the swine H1N1- and H3N2-challenged vaccinated pigs when compared to unvaccinated animals. A further decline in viral load was observed at 5 DPC where viral shedding was decreased by greater than 3 logs in vaccinated pigs receiving either the H1N1 or H3N2 virus challenge. Although the ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: Available online 16 November 2018Source: Veterinary MicrobiologyAuthor(s): Mengmeng Yu, Lixiao Xing, Fangfang Chang, Yuanling Bao, Suyan Wang, Xijun He, Jingfei Wang, shida Wang, Yongzhen Liu, Muhammad Farooque, Qing Pan, Yongqiang Wang, Li Gao, Xiaole Qi, Altaf Hussain, Kai Li, Changjun Liu, Yanping Zhang, Hongyu Cui, Xiaomei WangAbstractAvian metapneumovirus (aMPV), which has been reported in many countries, causes an acute upper respiratory tract disease in chickens and turkeys. Although aMPV was first detected in China in 1999, there has been no further effort to isolate and characterize the aMPV subt...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
ConclusionsThe HIIT programmes showed improvements in the variables studied, with interventions two or three times weekly. Therefore, they can be used in schools, as a strategy to combat the childhood obesity pandemic and HIIT can be use alongside with existing PE activities within the same lesson or in specific periods during day school.
Source: Journal of Exercise Science and Fitness - Category: Sports Medicine Source Type: research
Condition:   Influenza Interventions:   Biological: Quadrivalent influenza vaccine;   Biological: Trivalent influenza vaccine A;   Biological: Trivalent influenza vaccine B Sponsor:   Shanghai Institute Of Biological Products Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Conditions:   Influenza;   Influenza, Human;   Vaccine Reaction;   Influenza A;   Influenza Type B;   Influenza A H1N1;   Influenza A H3N2 Intervention:   Biological: Influenza Vaccine Recipients Sponsors:   Vanderbilt University Medical Center;   Human Vaccines Project Recruiting
Source: - Category: Research Source Type: clinical trials
(National Institute for Environmental Studies) As part of the cellular conservation of endangered species, our group initiated a primary cell culture project aimed at preserving endangered avian species in Japan, such as the Okinawa rail. However, primary cells cannot be cultured indefinitely because of cellular senescence and stresses caused by cell culture. To overcome these cell culture limitations, primary cells must be immortalized. As a result, we succeeded to obtain the immortalized avian cells with cell cycle regulation genes expression.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Contributors : Zhongxian Xu ; Diyan LiSeries Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Gallus gallusWe systematically investigated the lncRNA and mRNA temporal expression profile of the female chicken brain by high-throughput sequencing 8 stages across their entire lifespan. We identified and classified 39,907 putative lncRNAs, and predicted the potential biological functions of lncRNAs based on WGCNA. Temporal expression patterns were investigated based on a set of age-dependent genes, results showed that genes functioned in development, sy...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing Gallus gallus Source Type: research
lchat The influenza A virus (IAV) genome consists of eight single-stranded RNA segments. Each segment is associated with a protein complex, with the 3′ and 5′ ends bound to the RNA-dependent RNA polymerase (RdRp) and the remainder associated with the viral nucleoprotein. During transcription of viral mRNA, this ribonucleoprotein complex steals short, 5′-capped transcripts produced by the cellular DNA dependent RNA polymerase II (RNAPII) and uses them to prime transcription of viral mRNA. Here, we review the current knowledge on the process of IAV cap-snatching and suggest a requirement for...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
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