Connecticut reports its first death from Eastern equine encephalitis in years as the outbreak grows

A Connecticut resident infected with Eastern equine encephalitis has died in the state's first fatality from the disease since 2013, health officials said.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

Related Links:

This week I attended the Nipah Virus International Conference in Singapore, marking the discovery of the virus 20 years ago. It’s an opportune time to recall the events around the emergence of this deadly pathogen. An outbreak of respiratory disease and encephalitis in pigs during 1998 took place in Ipoh City of Perak state in […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information encephalitis fruit bat Hendra virus henipavirus Nipah virus pandemic Pteropus respiratory disease spillover viral viruses Source Type: blogs
Publication date: Available online 6 December 2019Source: Antiviral ResearchAuthor(s): Andrew M. Skidmore, Robert S. Adcock, Colleen B. Jonsson, Jennifer E. Golden, Dong-Hoon ChungAbstractVenezuelan equine encephalitis virus (VEEV) is an alphavirus that is endemic to the Americas. VEEV outbreaks occur periodically and cause encephalitis in both humans and equids. There are currently no therapeutics or vaccines for treatment of VEEV in humans. Our group has previously reported on the development of a benzamidine VEEV inhibitor, ML336, which shows potent antiviral activity in both in vitro and in vivo models of infection. In...
Source: Antiviral Therapy - Category: Virology Source Type: research
Abstract Venezuelan equine encephalitis virus (VEEV) is an alphavirus that is endemic to the Americas. VEEV outbreaks occur periodically and cause encephalitis in both humans and equids. There are currently no therapeutics or vaccines for treatment of VEEV in humans. Our group has previously reported on the development of a benzamidine VEEV inhibitor, ML336, which shows potent antiviral activity in both in vitro and in vivo models of infection. In cell culture experiments, ML336 inhibits viral RNA synthesis when added 2-4 h post-infection, and mutations conferring resistance occur within the viral nonstructural ...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Publication date: Available online 29 November 2019Source: Protein Expression and PurificationAuthor(s): Jae-Won Choi, Hyo-Ji Eom, Hak Yong KimAbstractJapanese encephalitis virus (JEV) is a member of the Flavivirus genus and has recently attracted attention as a high-risk pathogen in the Asia-Pacific region, with up to 30% mortality in the afflicted patients. Recent outbreaks of flavivirus-associated infections around the world have put the focus on non-structural protein 1 (NS1) as a candidate for diagnostic and vaccine researches on flaviviruses. Although the JEV NS1 protein has been expressed in eukaryotic cells, attemp...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
This year has seen a surprising upsurge in cases of a rare viral infection in humans. Specialists warn that we need a strategy to prevent an outbreak.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Officials from the National Institute of Allergy and Infectious Diseases note that, as of Nov. 12, there have been 36 confirmed cases of eastern equine encephalitis this year, 14 of which were fatal.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Jim Whitmore, fourth generation farmer in Eu Claire, Michigan died on Saturday, becoming the sixth victim of Eastern equine encephalitis in the state amid a historic outbreak in the US.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 15 November 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Ileana Z. Martínez, Claudia Pérez-Martínez, Luis M. Salinas, Juan F. García-Marín, Ramón A. Juste, Ana BalseiroABSTRACTSpanish goat encephalitis virus (SGEV) is a novel tick-borne flavivirus subtype, closely related to the flavivirus louping ill virus (LIV). SGEV caused a severe, acute and mortal neurological disease outbreak in northern Spain in a goat herd. In order to characterize the cell population in lesions and to determine the distribution of the inflammatory cells...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
Shalini Sunderam, Dewesh KumarIndian Journal of Community Medicine 2019 44(4):403-403
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
In this study, we investigated the antiviral effect of salvianolic acid B (SalB) on EV71. SalB is a major component of the Salvia miltiorrhiza root and has been shown to be an effective treatment for subarachnoid hemorrhages, and myocardial infarctions. HeLa cells were cultured in 12-well plates and treated with SalB (100 or 10 μg/mL) and 106 PFU/mL of EV71. SalB treatment (100 µg/mL) significantly decreased the cleavage of the eukaryotic eIF4G1 protein and reduced the expression of the EV71 capsid protein VP1. In addition, SalB treatment showed a dramatic decrease in viral infection, measured by immunofluorescenc...
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research
More News: Encephalitis | Health | Outbreaks