The case for absolute cardiovascular risk-based blood pressure-lowering treatment decisions: data from the SPRINT trial

Journal of Human Hypertension, Published online: 23 September 2019; doi:10.1038/s41371-019-0260-5The case for absolute cardiovascular risk-based blood pressure-lowering treatment decisions: data from the SPRINT trial
Source: Journal of Human Hypertension - Category: Cardiology Authors: Source Type: research

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CONCLUSIONS: Not all interventional procedures result in a mortality benefit. Medical therapy alone increases survival in many cardiac diseases. PMID: 32083425 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - Category: Cardiology Tags: Minerva Cardioangiol Source Type: research
Authors: Nuotio J, Suvila K, Cheng S, Langén V, Niiranen T Abstract Observational and interventional studies have unequivocally demonstrated that "present", i.e. single-occasion, blood pressure is one of the key determinants of cardiovascular disease risk. Over the past two decades, however, numerous publications have suggested that longitudinal blood pressure data and assessment of long-term blood pressure exposure provide incremental prognostic value over present blood pressure. These studies have used several different indices to quantify the overall exposure to blood pressure, such as time-aver...
Source: Annals of Medicine - Category: Internal Medicine Tags: Ann Med Source Type: research
Conclusions Surufatinib demonstrated promising efficacy with a tolerable and manageable safety profile for patients with locally advanced or metastatic MTC, RAI-refractory DTC, or locally advanced, unresectable recurrences unable to receive RAI. PMID: 32075524 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
ConclusionsThere are elevated levels of risk for CVD in some athletes, primarily football players. Lifestyle behaviours associated with elite athleticism, particularly football linemen potentially expose players to greater metabolic and CVD risk, which is not completely offset by sport participation.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Sarah Novotny, Nicole Lee-Plenty, Kedra Wallace, Wondwosen Kassahun-Yimer, Aswathi Jayaram, James A. Bofill, James N. MartinAbstractObjectiveTo determine the prevalence of acute kidney injury (AKI), placental abruption and postpartum hemorrhage in patients with preeclampsia or HELLP syndrome.Study designA retrospective study of patients with preeclampsia or HELLP syndrome treated at the University of Mississippi Medical Center from January 2000 through December 2010.Main outcome measuresRelationships among the obstetric complications of place...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Laura A Magee, Joel Singer, Terry Lee, Richard J McManus, Sarah Lay-Flurrie, Evelyne Rey, Lucy C Chappell, Jenny Myers, Alexander G Logan, Peter von DadelszenAbstractObjectiveTo examine the relationship between pregnancy outcomes and BP level and variability.DesignSecondary analysis of CHIPS trial data (Control of Hypertension In Pregnancy Study, NCT01192412).SettingInternational.Population or sampleWomen with chronic or gestational hypertension.MethodsBP measurement was standardised in outpatient clinics. Adjusted (including for allocated gr...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Cecilia Villalain, Ignacio Herraiz, Borja Cantero, Soledad Quezada, Ana Lopez, Elisa Simón, Alberto GalindoAbstractObjectivesThe optimal timing for delivery in non-severe late-preterm (34 + 0–36 + 6 weeks) preeclampsia (PE) is uncertain. It is attempted to reach term pregnancy safely but current clinical and analytical parameters fail to determine which cases will develop severe features that require preterm delivery. We aim to establish if angiogenic biomarkers may identify cases that would benefit from ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Mohamed Rezk
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Ellie Proussaloglou, Ariel Mueller, Ruby Minhas, Sarosh RanaAbstractObjectivesHypertensive disorders of pregnancy are a leading cause of maternal morbidity and mortality. Although acute severe hypertension carries with it a poor prognosis, treatment is often delayed and not universal.Study designA total of 654 patients were assessed for the impact of hypertensive disorders of pregnancies on maternal and fetal morbidity and divided into three groups: normotensive (Group I, N = 306), non-severe hypertension (Group II, N = 24...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionAspirin resistance was found in a considerable part of the participants. Considerable variation between participants, within participants over time and between the different devices was found. Prevalence of aspirin resistance during pregnancy differs from after pregnancy. More research on aspirin resistance and clinical obstetric outcome is needed.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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