Neovaginoplasty using Nile Tilapia Fish Skin as a new biological graft in patients with Mayer-Rokitansky-Küster-Hauser syndrome

Publication date: Available online 20 September 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Maria Tereza Pinto Medeiros Dias, Andreisa Paiva Monteiro Bilhar, Livia Cunha Rios, Bruno Almeida Costa, Edmar Maciel Lima Júnior, Ana Paula Negreiros Nunes Alves, Zenilda Vieira Bruno, Manoel Odorico de Moraes Filho, Leonardo Robson Pinheiro Sobreira BezerraABSTRACTMayer–Rokitansky–Kuster–Hauser syndrome is the second most common cause of primary amenorrhea, trailing only gonadal dysgenesis. In patients who failed dilation therapy, neovaginoplasty is an appropriate treatment option. Several biomaterials have been used in this procedure, including peritoneum, amnion, skin grafts and myocutaneous flaps. Nile Tilapia Fish Skin has non-infectious microbiota, morphological structure comparable to human skin, and high in vivo bioresorption. In addition, it showed good outcomes when used as a xenograft for burn treatment. Thus, we suggest it as a new biological graft for vaginal agenesis management. In this descriptive study (Canadian Task Force classification III), neovaginoplasty using Nile Tilapia Fish Skin offered three patients an anatomical and functional neovagina via a simple method with potential long-term effectiveness. When postsurgical dilation was performed correctly, a vaginal length greater than 6 cm was maintained at 180 days follow-up. Histological and immunohistochemical analyses revealed presence of stratified squamous epithelium...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research

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Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
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Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
This study contributes to a better understanding of the IL-4/13A system in salmon, which as a key axis for Th2 response may be involved not only in pathogen elimination but also in adaptive immune repair that seems critical tolerance to infectious diseases.
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
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Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 14 November 2019Source: Fish &Shellfish ImmunologyAuthor(s): Yan-Ying Nian, Bo-Kun Chen, Jing-Jing Wang, Wei-Tao Zhong, Yan Fang, Zan Li, Qiu-Sheng Zhang, Dong-Chun YanAbstractInfectious hypodermal and haematopoietic necrosis virus (IHHNV) is a major viral pathogen in cultured penaeid shrimp. IHHNV has many hosts, mainly including crustaceans. It has recently been reported that Procambarus clarkii can be infected by IHHNV. In the present study, we studied the hepatopancreas of P. clarkii by transcriptome high-throughput sequencing to analyze the response of P. clarkii to IHHNV infecti...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 14 November 2019Source: Fish &Shellfish ImmunologyAuthor(s): Chengzhang He, Ruijuan Hao, Yuewen Deng, Chuangye Yang, Xiaodong DuAbstractThe pearl oyster, Pinctada fucata martensii, produces high-quality pearls. During pearl production, excess immune and inflammatory response after transplantation will lead to nucleus rejection, pearl sac formation failure, and death of the host pearl oyster. The hemocyte transcriptome and fatty acid (FA) contents in the adductor muscle before and after transplantation were analyzed to investigate the response of pearl oyster P. f. martensii to allogra...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
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Source: Medicina Intensiva - Category: Intensive Care Source Type: research
Publication date: November 2019Source: European Urology Supplements, Volume 18, Issue 11Author(s): M. Alsawi, H. Burns, R. Sohail-Khan, J. De Souza
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
CONCLUSION: Australian law currently requires legal medicinal cannabis use to follow specific, regulated pathways that limit prescription by this method; however, self-reported illicit use of cannabis remains relatively common in Australian women with endometriosis. Women report good efficacy of cannabis in reducing pain and other symptoms, with few adverse effects reported. Further clinical research is warranted to determine the effectiveness of cannabis in managing endometriosis symptoms. In locations where medicinal cannabis is more accessible, there remains a paucity of evidence for its clinical efficacy with endometri...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Mayer –Rokitansky–Kuster–Hauser syndrome is the second most common cause of primary amenorrhea, trailing only gonadal dysgenesis. In patients who failed dilation therapy, neovaginoplasty is an appropriate treatment option. Several biomaterials have been used in this procedure, including peritoneum, amnion, skin grafts and myocutaneous flaps. Nile Tilapia Fish Skin has non-infectious microbiota, morphological structure comparable to human skin, and high in vivo bioresorption. In addition, it showed good outcomes when used as a xenograft for burn treatment.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: INSTRUMENTS AND TECHNIQUES Source Type: research
More News: Amenorrhea | Burns | Canada Health | Fish | MRKH Syndrome | OBGYN | Skin | Skin Graft | Study