Minimizing control group allocation in randomized trials using dynamic borrowing of external control data - An application to second line therapy for non-small cell lung cancer.

Conclusion: Dynamic borrowing using Bayesian hierarchical models with uninformative priors represents a novel approach to utilizing external controls for comparative estimates using single arm evidence. PMID: 31538129 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/31538129?dopt=Abstract

Source: Clinical Lung Cancer - September 22, 2019 Category: Cancer & Oncology Authors: Dron L, Golchi S, Hsu G, Thorlund K Tags: Contemp Clin Trials Commun Source Type: research