FLUCELVAX QUADRIVALENT (PREFILLED SYRINGE) (Influenza A Virus A/Idaho/07/2018 (H1n1) Antigen (Mdck Cell Derived, Propiolactone Inactivated, Influenza A Virus A/Indiana/08/2018 (H3n2) Antigen (Mdck Cell Derived, Propiolactone Inactivated), Influenza B Virus B/Singapore/Inftt-16-0610/2016 Antigen (Mdck Cell Derived, Propiolactone Inactivated), Influenza B Virus B/Iowa/06/2017 Antigen (Mdck Cell Derived, Propiolactone Inactivated)) Injection, Suspension FLUCELVAX QUADRIVALENT (MULTI-DOSE VIAL) (Influenza A Virus A/Idaho/07/2018 (H1n1) Antigen (Mdck Cell Derived, Propiolactone Inactivated, Influenza A Virus A/Indiana/08/2018 (H3n2) Antigen (Mdck Cell Derived, Propiolactone Inactivated), Influenza B Virus B/Singapore/Inftt-16-0610/2016 Antigen (Mdck Cell Derived, Propiolactone Inactivated), Influenza B Virus B/Iowa/06/2017 Antigen (Mdck Cell Derived, Propiolactone Inactivated)) Injection, Suspension Seqirus, Inc.

Updated Date: Fri, 20 Sep 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts

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A recent study in this journal compared codon usage among NA subtypes (N1, N2, N6, and N8)  of H5Nx highly pathogenic avian influenza A viruses (HPAIVs) and suggested that codon usage in N1 subtype is better adapted to its host than the epidemic NA subtypes (N6 and N8), which had fewer number of human cases compared to the N1 subtype.1 To date, there are 18 known HA subtypes (H1-H18) and 11 known NA subtypes (N1-N11)2. However, only N1 and N2 subtypes have been reported to cause pandemics (H1N1 for the 1918 and 2009 pandemics; H2N2 for the 1957 pandemic; and H3N2 for the 1968 pandemic) or seasonal outbreaks in humans3.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
Abstract During May 19-September 28, 2019,* low levels of influenza activity were reported in the United States, with cocirculation of influenza A and influenza B viruses. In the Southern Hemisphere seasonal influenza viruses circulated widely, with influenza A(H3) predominating in many regions; however, influenza A(H1N1)pdm09 and influenza B viruses were predominant in some countries. In late September, the World Health Organization (WHO) recommended components for the 2020 Southern Hemisphere influenza vaccine and included an update to the A(H3N2) and B/Victoria-lineage components. Annual influenza vaccination i...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
CONCLUSIONS: Influenza-associated mortality was substantial during this period, especially in the elderly. By subtype, influenza A(H3N2) virus made the largest contribution to influenza-associated mortality. PMID: 31588700 [PubMed - in process]
Source: Journal of Preventive Medicine and Public Health - Category: International Medicine & Public Health Tags: J Prev Med Public Health Source Type: research
This study illustrates how recurrent influenza infections increase the co-infection risk and facilitate evolutionary jumps by successive gene exchanges. It recalls the importance of appropriate biosecurity measures inside holdings to limit virus persistence and interspecies transmissi ons, which both contribute to the emergence of new potentially zoonotic viruses.
Source: Veterinary Research - Category: Veterinary Research Source Type: research
Updated Date: Thu, 03 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Publication date: Available online 30 September 2019Source: Brain, Behavior, and ImmunityAuthor(s): Alexandra Ledo, David Schub, Clemens Ziller, Martin Enders, Tanja Stenger, Barbara C. Gärtner, Tina Schmidt, Tim Meyer, Martina SesterAbstractCompliance of elite athletes with vaccination recommendations is low mainly based on concerns about side-effects and perceived poor vaccine efficacy due to continued physical training. We therefore employed seasonal influenza vaccination to investigate the effect of regular physical training on vaccine-induced cellular and humoral immunity in elite athletes and controls.Lymphocyte...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Updated Date: Tue, 01 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Updated Date: Tue, 01 Oct 2019 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
In this study, we demonstrated that the ability to bind the Neu5Gc-terminated receptor is related to the amino acid 145: viruses of years 1972 –1999 with Lysl45bindto the receptor, whereas viruses with Asnl 45 do not. Sporadic appearance and disappearance of the ability to bind Neu5Gc oligosaccharides and the absence of Neu5Gc in the composition of human glycoconjugates indicate the non-adaptive nature of this ability. It was previously shown that unlike H1N1 viruses, H3N2 viruses of years 1968–1989 did not distinguish between Neu5Acα2-6Galβ1-4Glc (6′SL) and Neu5Acα2-6Galβ1-4GlcNAc (...
Source: Biochemistry (Moscow) - Category: Biochemistry Source Type: research
r M Abstract Compliance of elite athletes with vaccination recommendations is low mainly based on concerns about side-effects and perceived poor vaccine efficacy due to continued physical training. We therefore employed seasonal influenza vaccination to investigate the effect of regular physical training on vaccine-induced cellular and humoral immunity in elite athletes and controls. Lymphocyte subpopulations and vaccine-specific T-cells were quantified and functionally characterized from 45 athletes and 25 controls before, and 1, 2 and 26 weeks after vaccination. Moreover, influenza-specific antibodies and their ...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
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