The developing gut-lung axis: postnatal growth restriction, intestinal dysbiosis, and pulmonary hypertension in a rodent model.

CONCLUSION: PNGR causes intestinal dysbiosis and PH. Treatment with DSM 17938 prevents PNGR-associated RVH and PH. Changes in the developing intestine and intestinal microbiota impact the developing lung vasculature and RV. PMID: 31537010 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31537010?dopt=Abstract

Source: Pediatric Research - September 18, 2019 Category: Pediatrics Authors: Wedgwood S, Warford C, Agvatisiri SR, Thai PN, Chiamvimonvat N, Kalanetra KM, Lakshminrusimha S, Steinhorn RH, Mills DA, Underwood MA Tags: Pediatr Res Source Type: research