Medications for opioid addiction treatment are underused, researchers say
Three medications to help fight opioid addiction are widely underused in treatment of people with opioid use disorder, according to a new study.
Publication date: Available online 20 October 2019Source: International Journal of PsychophysiologyAuthor(s): Eliana Vassena, Filip Van Opstal, Ingeborg Goethals, Tom VergutsAbstractThe ability to exert control has been widely investigated as a hallmark of adaptive behaviour. Dopamine is recognized as the key neuromodulator mediating various control-related processes. The neural mechanisms underlying the subjective perception of being in control, or Locus of Control (LOC) are however less clear. LOC indicates the subjective tendency to attribute environmental outcomes to one's actions (internal LOC) or instead to external ...
Authors: Arezoomandan R, Aliaghaei A, Khodagholi F, Haghparast A Abstract Glial glutamate transporters (GLT-1) is responsible for glutamate homeostasis. GLT-1 expression and glutamate uptake can be affected by addictive drugs and can be used as a target in addiction pharmacotherapy. It has been shown that minocycline, an antibiotic with anti-inflammatory, and neuroprotective properties, can upregulate the expression of GLT-1. In the present study, in morphine-dependent rats, the effect of minocycline on expression of GLT-1 in nucleus accumbens was investigated by immunohistochemistry. The expression of GLT-1 signif...
Four large drug companies reached a last-minute $260 million legal settlement on Monday over their role in the U.S. opioid addiction epidemic, striking a deal with two Ohio counties to avert the first federal trial over the crisis.
Talks to reach a settlement of thousands of lawsuits stemming from the U.S. opioid addiction crisis could resume as soon as Tuesday, an attorney for local governments said on Monday.
Teva and distributors’ deal came as first federal trial on US addiction crisis was due to open
Condition: Heroin Dependence Intervention: Behavioral: methadone induced memory retrieval-extinction procedure Sponsor: National Institute on Drug Dependence, China Completed
Condition: Addiction Intervention: Device: ASC Sponsor: Assistance Publique - Hôpitaux de Paris Recruiting
Condition: Smartphone Users, Smartphone Addiction, Anxiety, and Skin Conductance Intervention: Device: social media stimuli (Line app) Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital Completed
Condition: Cancer Interventions: Other: Psychosocial Navigator; Other: Communication of Summary Profile Sponsors: The Hospital for Sick Children; Centre for Addiction and Mental Health Active, not recruiting
Publication date: Available online 21 October 2019Source: Journal of Psychiatric ResearchAuthor(s): Chen Lin, Bo-Yu Wong, Men-Tzung Lo, Yu-Chuan Chiu, Yu-Hsuan LinAbstractIllicit drug use contributes to substantial morbidity and mortality. Drug scheduling, a legal measure in drug enforcement, is often structured as a hierarchy based on addiction tendency, abuse trends, and harm, but may lack data-driven evidence when classifying substances. Our study aims to measure addiction tendency and use trends based on real-world data. We used the open access database of National Police Agency, Ministry of the Interior in Taiwan and ...