Epilepsy patients with and without perceived benefit from vagus nerve stimulation: A long-term observational single center study

ConclusionHalf of the patients had not perceived clear benefit from VNS, and all but one terminated VNS without worsening of seizures within one year. The true outcome of long-term VNS is difficult to assess in real-world practice. The effect may be overestimated due to confounding factors, particularly the common introduction of novel AEDs and the natural course of the disorder. Patients without perceived benefit from long-term VNS should not routinely remain on treatment and be subject to undue generator re-implantations.
Source: Seizure - Category: Neurology Source Type: research