Childhood cancer: unequal progress

Publication date: 21–27 September 2019Source: The Lancet, Volume 394, Issue 10203Author(s): The Lancet
Source: The Lancet - Category: General Medicine Source Type: research

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Growth failure concerns 10-20% of the survivors of childhood cancer. The present knowledge is insufficient to predict the risks, especially concerning chemo- and radiotherapy treatment details. Our study aimed to define the significant determinants of a small adult height.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
In 2016, low- and middle-income country (LMIC) outreach efforts within the executive committee of the Pediatric Radiation Oncology Society (PROS) were integrated into the International Society of Pediatric Oncology ’s (SIOP) Pediatric Oncology in Developing Countries (PODC) organization and formalized as the PROS-LMIC working group. PROS-LMIC recognizes the proportionally larger burden of childhood cancer incidence, mortality, and morbidity that exists in low- and middle-income countries.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
The QUARTET project from SIOPE, in collaboration with the EORTC, aims to standardise radiotherapy in order to improve outcomes in tumour control and quality of life (QoL) for childhood, adolescent and young adult cancer survivors. Variation in the selection and delineation of normal tissue structures can have significant implications for both target coverage and organ at risk (OAR) sparing. Guidelines are required for more homogenous datasets, which are essential to yield meaningful conclusions from clinical trials.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
Conditions:   Hepatocellular Carcinoma, Childhood;   Hepatocellular Carcinoma;   Liver Cancer;   Liver Cancer Pediatric Intervention:   Drug: Pembrolizumab Sponsor:   Allison O'Neill Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Whether or not to circumcise your baby is a personal decision often determined by a variety of social, cultural, medical, or religious circumstances. Parents have the right to choose what they believe is best for their newborn and typically undergo extensive research before deciding what’s best for their family. So, what is the process of circumcision? Once parents decide to move forward, about an hour before the procedure, doctors use an anesthetic to numb the baby’s penis. The area is then sterilized and the excess skin on the penis is clamped and cut. Finally, the physician covers the penis in bandages or ga...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies pregnancy Source Type: blogs
Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Source Type: research
CCR Grand Rounds Dr. Jabado ’ s research focuses on elucidating genetic signatures of pediatric astrocytomas and examining how they compare to adults. These are deadly brain tumors that originate in the brain and include glioblastomas (GBM, the highest grade of astrocytomas), which are one of the deadliest cancers in humans. Her group uncovered that pediatric high-grade astrocytomas (HGA) are molecularly and genetically distinct from adult tumors. They also identified a new molecular mechanism driving pediatric HGA, namely recurrent somatic driver mutations in the tail of histone 3 variants (H3.3 and H3.1). These mut...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
ConclusionOur study contributes to understanding how families of a child with cancer make treatment decisions. Families tend to rely on doctors to make treatment decisions, but often seek additional information to help them feel involved in the decision process. Findings highlight that decision-making in pediatric oncology should focus on involving families in the deliberation phase, rather than just determination of choice.
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
MONDAY, Oct. 21, 2019 -- For adult survivors of childhood acute lymphoblastic leukemia (ALL), exercise intolerance is associated with worse neurocognitive outcomes, according to a study published online Oct. 21 in Cancer. Nicholas S. Phillips, M.D.,...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
MONDAY, Oct. 21, 2019 -- Boosting exercise capacity may protect the mental functioning of childhood leukemia survivors, according to a new study. Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Due to their disease and...
Source: - Daily MedNews - Category: General Medicine Source Type: news
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