Comparison of Frontline Breast Cancer Drugs Reveals Important Differences
No abstract available
Abstract The development of metastatic disease accounts for the vast majority of cancer-related deaths in solid tumor malignancies. Distant metastases primarily develop as a result of tumor cell dissemination through the circulatory system. PMID: 31605228 [PubMed - in process]
[Ghanaian Times] Women diagnosed with breast cancer should not allow men to stand in their way of treatment, the Head of Breast Care Unit at the Korle Bu Teaching Hospital, Dr Florence Dedey, has advised.
This article reviews the major pathways by which adrenal steroids are converted to the potent male sex hormones, testosterone (T) and 5α-dihydrotestosterone (5α-DHT) and the discrete enzyme isoforms involved in castration resistant prostate cancer. Previous studies have mainly utilized radiotracers to investigate these pathways but have not used prevailing concentrations of precursors found in castrate male human serum. In addition, the full power of stable-isotope dilution liquid chromatography tandem mass spectrometry has not been applied routinely. Furthermore, it is clear that adaptive responses occur in th...
NICE approves rucaparib for use on NHS Related items fromOnMedica Drug for hereditary ovarian cancer approved Cancer drugs to be re-evaluated Red tape delaying availability of new cancer drugs Is crowdfunding for cancer patients paying for ‘quackery’? NICE rejects breast cancer drug for NHS funding
Molecules, Vol. 24, Pages 3693: Metabolism, Transport and Drug–Drug Interactions of Silymarin Molecules doi: 10.3390/molecules24203693 Authors: Xie Zhang Zhang Yuan Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common products widely used in the phytotherapy of liver diseases. They also have promising effects in protecting the pancreas, kidney, myocardium, and the central nervous system. However, inconsistent results are noted in the different clinical studies due to the low bioavailability of silymarin. Extensive studies were conducted to explore the metabo...
CONCLUSIONS IQGAP3 may be a potential target gene for Kaempferol in the treatment of BC, and upregulation of IQGAP3 inhibits Kaempferol-induced apoptosis in BC cells by ERK1/2 signaling activation. Targeting IQGAP3 may contribute to the study of natural phytochemicals as anti-tumor drugs in BC. PMID: 31605603 [PubMed - in process]
CONCLUSION: Audio-visual navigation enables to significantly reduce the treatment time in comparison with DIBH without A-V feedback. PMID: 31602046 [PubMed - as supplied by publisher]
[New Times] October is breast cancer awareness month. And whereas the spotlight is commonly put on breast cancer in women, male breast cancer is a concern that needs immediate attention.
Publication date: Available online 11 October 2019Source: Biosensors and BioelectronicsAuthor(s): Weiqing Xu, Lei Jiao, Huarong Ye, Zhenzhong Guo, Yu Wu, Hongye Yan, Wenling Gu, Dan Du, Yuehe Lin, Chengzhou ZhuAbstractEstrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) are the three crucial biomarkers for the clinical diagnosis of breast cancer. Sensitive and precise detection of ER, PR, and HER2 is of great significance for the diagnosis of breast cancer. Herein, through a simple solvent-induced self-assembly process, the self-carried allochroic nanoparticles were prepar...